Electrospun Aligned PCL/Gelatin Scaffolds Mimicking the Skin ECM for Effective Antimicrobial Wound Dressings
1Department of Mechanical Engineering, Center for Nanotechnology and Sustainability, National University of Singapore, 117581, Singapore, Singapore
2Ocular Infections and Antimicrobials Research Group, Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower, 169856, Singapore, Singapore
3Institute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), #08-03, 2 Fusionopolis Way, Innovis, 138634, Singapore, Singapore
4Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore, Singapore
5Department of Pharmacy, National University of Singapore, 18 Science Drive 4, 117543, Singapore, Singapore
6Academic Clinical Program in Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, 169857, Singapore, Singapore
7National Skin Centre, 1 Mandalay Road, 308205, Singapore, Singapore
8Department of Materials and Polymer Engineering, Faculty of Engineering, Hakim Sabzevari University, 9617976487, Sabzevar, Iran
9Faculty of Dentistry, National University of Singapore, 119085, Singapore, Singapore
10ORCHIDS: Oral Care Health Innovations and Designs Singapore, National University of Singapore, Singapore, 119085, Singapore, Singapore
11Department of Biomedical Engineering, University of North Carolina at Chapel Hill, 27514, Chapel Hill, NC, USA
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Erfan Rezvani Ghomireceived his B.Sc. in Chemical Engineering from Isfahan University of Technology (IUT), Iran, in 2016, and his M.Sc. in Polymer Engineering from IUT, Iran, in 2019. During his M.Sc., he worked on the development of self-healing polymeric coatings. He is currently a Ph.D. candidate at National University of Singapore (NUS) under Prof. Seeram Ramakrishna’s supervision. His current research interests mainly focus on the electrospinning and 3D printing of polymers for biomedical applications.
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Rajamani Lakshminarayananis working the Co-Head of Ocular Infections and Anti-Microbials Research Group at the Singapore Eye Research Institute. He also holds a joint appointment as Associate Professor at the Department of Pharmacy at the National University of Singapore. For more than 20 years as a researcher, he has made substantial contributions in the areas of biomineralization, antimicrobial peptide design and topical delivery of antimicrobials, protein-protein/lipid interactions, extracellular matrix assembly and protein aggregation diseases. The long-term goal of his research is to translate the projects on combating antimicrobial resistance in collaboration with local and overseas collaborators. More information can be found at: https://www.snec.com.sg/research-innovation/research-groups-platforms/research-groups/anti-infectives and https://scholar.google.com.sg/citations?user=viRiE3gAAAAJ&hl=en.
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Vijila Chellappanis a Senior Scientist in the Institute of Materials Research and Engineering, Agency for Science, Technology, and Research (A-STAR), Singapore. She is experienced over 20 years with strong expertise on various optoelectronic device technologies (Photovoltaics, Displays, Lasers), Material systems (semiconducting polymers, oxides, transition metal dichalcogenides, conducting composites) and Transient optical/electrical characterization capabilities including high-throughput optical methodologies for machine learning enabled process optimization. She received her Ph.D. degree in Physics from Anna University, India, in 2001, and carried out postdoctoral research at Åbo Academy University, Turku, Finland from 2001 to 2002. More details: https://scholar.google.com.sg/citations?user=zrj38lkAAAAJ&hl=en.
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Navin Kumar Vermareceived his PhD and postdoctoral training in Clinical Medicine from Trinity College Dublin, Ireland. He is currently an Assistant Professor of Immunology and Cell Biology at the Lee Kong Chan School of Medicine, Nanyang Technological University Singapore (NTU). He is leading a multidisciplinary research team focused on T-cell immunology in health and diseases. In addition to antitumor T-cell immunity, his research interests include lymphoid cancer, skin immunology, and wounds.
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Amutha Chinnappanreceived her PhD degree in organic nanomaterials using ionic liquids for energy applications from Myongji University, South Korea in 2013. She then worked as a BK21 Postdoctoral Fellow until 2015, and after that became an Assistant Professor (Research) at the Department of Energy, Science and Technology, Myongji University. She is currently working as a Senior Research Fellow at the Center for Nanotechnology & Sustainability, National University of Singapore. She has published 90+ peer reviewed scientific research articles in reputed international journals (https://scholar.google.com/citations?hl=en&user=WsDtitQAAAAJ&view_op=list_works). Her current research interests include green chemistry, circular economy, plastic recycling, conducting cables/ wires, smart textiles, wearable/flexible electronics, and ionic liquid-based functional nanomaterials for energy applications.
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Rasoul Esmaeely Neisianyreceived his Ph.D. in Polymer Engineering from the Isfahan University of Technology in 2017 and he carried out his sabbatical at the National University of Singapore. He conducted his postdoctoral research at the Isfahan University of Technology. He has been a member of the faculty in the Materials and Polymer Engineering Department at Hakim Sabzevari University since 2019 with a focus on developing self-healing polymeric materials and tissue engineering.
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Kottaiswamy Amuthavallireceived her PhD in Biochemistry from the University of Madras, India, in 2021. She is currently pursuing her postdoctoral research training at the Lee Kong Chain School of Medicine, Nanyang Technological University Singapore (NTU). She has expertise in cell and molecular biology, oncology, miRNA biomarker, and drug discovery. Currently, her primary research focus is to understand T-cells involvement in wound healing.
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Zhi Sheng Pohreceived his received his B.Sc. (Honors) with highest distinction in Biological Sciences from Nanyang Technological University Singapore (NTU) in 2020. He is currently a Ph.D. candidate at the Lee Kong Chan School of Medicine (NTU) under the supervision of Assistant Professor Navin Kumar Verma. His research goal is to understand molecular cues associated with cancer aggressive phenotypes and chemoresistance.
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Brandon Han Siang Wongreceived his received his B.Sc. (Honors) with highest distinction in Biological Sciences from Nanyang Technological University Singapore (NTU) in 2020. He is currently a Ph.D. candidate at the Lee Kong Chan School of Medicine (NTU) under the supervision of Assistant Professor Navin Kumar Verma. His current research, supported by the Interdisciplinary Graduate Programme, NTU Institute for Health Technologies (HealthTech NTU), is aimed at understanding functional impact of high extracellular potassium on human T-cells.
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Nileshkumar Dubeyis a tenure-track Assistant Professor in the Faculty of Dentistry, National University of Singapore. He received a Bachelor of Dentistry (BDS) degree from Maharashtra University of Health Sciences, as well as a doctorate and post-doctoral fellowship in Tissue Engineering and Regenerative Medicine from the National University of Singapore and the University of Michigan, respectively. His research interest includes the use of Biofabrication,3D bioprinting and Electrospinning technology for tissue regeneration and drug delivery applications. Recently, he has been honored with Interstellar initiative Award by the New York Academy of Sciences and the Japan Agency for Medical Research and Development that recognizes and connects the world's most promising Early Career Investigators.
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Roger Narayanis a Professor in the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. He has authored over two hundred publications as well as several book chapters on processing, characterization, and modeling of biomedical materials. Dr. Narayan has also edited several books, including the handbook Materials for Medical Devices (ASM International), the textbook Biomedical Materials (Springer), the Encyclopedia of Sensors and Biosensors (Elsevier), and the Encyclopedia of Biomedical Engineering (Elsevier). He has been elected as Fellow of the Materials Research Society, ASM International, American Ceramic Society, AAAS, and AIMBE.
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Professor Seeram Ramakrishna, FREng, Everest Chairis a world-renowned scholar at the National University of Singapore (https://blog.nus.edu.sg/seeram/). He is regarded as the guru of electrospinning and applications (http://nart2020.com/conferenceinfo/). He pioneered nanotechnology and biomedical engineering in Asia. He is named among the World’s Most Influential Minds (Thomson Reuters); and the Top 1% Highly Cited Researchers in materials science as well as cross-field categories (Clarivate Analytics). He is an elected Fellow of UK Royal Academy of Engineering; Singapore Academy of Engineering; Indian National Academy of Engineering; and ASEAN Academy of Engineering & Technology. He is the Editor-in-Chief of Springer NATURE journal Materials Circular Economy. He is the Biomaterials Editor of Elsevier journal Current Research in Biomedical Engineering. He is an Associate Editor of Advanced Fiber Materials journal, and eScience journal (https://scholar.google.com.sg/citations?view_op=view_org&hl=en&org=83442941566286721; https://www.linkedin.com/in/seeram-ramakrishna/).
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