Cellular therapy potential in the treatment of ischemic stroke in experiment

I. B. Sokolova , N. N. Zin’kova , A. A. Bilibina , P. V. Kruglyakov , E. G. Gitlerovich , D. G. Polyntsev , V. A. Ottelin

Genes & Cells ›› 2007, Vol. 2 ›› Issue (4) : 54 -62.

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Genes & Cells ›› 2007, Vol. 2 ›› Issue (4) : 54 -62. DOI: 10.23868/gc139200
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Cellular therapy potential in the treatment of ischemic stroke in experiment

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Abstract

The possibility and efficacy of intravenous transplantation of mesenchymal stem cells after ischemic stroke in rats were studied. This therapeutic method has been shown to activate the proliferation of endogenous neuronal stem cells in the subependimal area of the brain lateral ventricles and angiogenesis in the nearby area, promote the neuron vitality within the same area, decrease the extent of brain tissue damaged and hasten recovery of the cognitive functions in animals.

Keywords

multipotent mesenchymal stem cells / ischemic stroke/cerebral infarction / neurons

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I. B. Sokolova, N. N. Zin’kova, A. A. Bilibina, P. V. Kruglyakov, E. G. Gitlerovich, D. G. Polyntsev, V. A. Ottelin. Cellular therapy potential in the treatment of ischemic stroke in experiment. Genes & Cells, 2007, 2(4): 54-62 DOI:10.23868/gc139200

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