Formation of a back pain as consequence of an undifferentiated dysplasia of a connecting tissue at 164 pupils who are engaged in ballet and rhythmic gymnastics, with the diagnosis hypermobility of joints is studied. Hypermobility in the field of a backbone led at the given pupils to formation of a pain against functional blocks аnd with the certain anamnesis and objective clinical picture.

For evaluating functional state of hematoenchephalic barrier 80 newborns of different gestational period with hemolytic disease of the newborns (HDN) and 30 infants with conjugated jaundice in the neonatal dynamics were examined. The function of hematoenchephalic barrier was defined by concentration of glyofibrillar acid protein and neurospecific enolase by polarization fluoroimmunoassay method. In the result of the newborns' follow-up there was revealed a precise correlation between their state and the level of neuro-specific proteins, being the index of penetration level of hematoencephalic barrier. In newborns with conjugated jaundice the expressed clinical manifestations are connected on one hand with the combined effect of acute and/or chronic hypoxia, and on the other hand with bilirubin toxic action, affecting hematoencephalic barrier, causing dismetabolic lesions of neurons.

With the help of formal questionnaires 80 doctors (50 psychiatrists and 30 drug treatment doctors) and 200 psychiatric patients with comorbid addictive disorders were interviewed. Decrease of the role of drug treatment services and adequate opportunity to provide specialized assistance to this group of patients by psychiatrists were shown.

There was studied titre of antibodies to the acetylcholine receptor in patients with myasthenia serum at pre-surgery stage. In patients with myasthenia with hyperplasia of thymus gland the average level of antibodiacetylcholine receptor exceeded 4 times the normal values and in patients with thymoma- 8 times. Level of antibodies to AChR did not correlate with the severity of myasthenia and myasthenia, combined with thymoma but tended to increase with the deterioration in specific cases. With a history of the disease more than a year there is a sharp increase in antibody levels in patients' serum, which leads to the progression of the disease.

Clinical-psychopathological and pathopsychological investigation of 204 patients showed "anti-therapeutic" influence of the acquired life experience with anxiety disorder. This experience was identified as anxiopathia and was considered to be one of the reasons of transformation of generalized anxiety disorder into the chronic form.

Social characteristics and emotional state were investigated during in-vitro fertilization (IVF) cycles in 176 women with tube-peritoneal infertility. There was established a negative influence on pregnancy probability after in vitro fertilization of emotional state and social peculiarities of women: emotional lability, dependence on environment, demonstrativeness, attempts for responsibility avoiding, concentrated control of emotion manifestations and behavior, passivity, fatigue, absence of need for communication.

In the article clinical characteristic of personal infantilism in children with congenital heart disease is presented. The significant biological, social and environmental factors influencing development and dynamics of detained age mental development as personal infantilism in children with congenital heart disease are analyzed. Objects of psychocorrectional measures are defined; programs of the psychotherapeutic help to children and psychological support of parents are developed.

A comparative clinical, psycho-neurological and pathopsychological analysis of therapeutical effectiveness of the developed complex and combined reconstructive technologies of reduction of long-term effects of mild intracranial injuries in 106 combatants have been made. Possibilities of pharmacologic effect potentiation in the form of common magnetic therapy are shown.

The Neuroimaging differential diagnosis of initial discirculatory encephalopathy and consequences of light repeated craniocerebral injuries remains ambiguous and difficult in the interpretation plan for the practical neurologist. Changes according to the data of the magnetic resonance imaging of brain in patients with the post-traumatic consequences and with the initial vascular encephalopathy sometimes have the similar nature of disturbances, which are rather complicated for expert and clinical neurology. The discriminate analysis of the MRI-indices of the linear dimensions of the ventricles of the brain and of subarachnoid spaces reliably distinguishes cerebral post-traumatic and vascular violations.

To evaluate adaptive abilities of senior schoolchildren, suffering from diabetes mellitus, type I, there was performed a complex investigation of adaptation mechanisms at rest and during functional test. There was revealed a correlation between the obtained indices and manifestation of disadaptation syndrome.

The article is concerned with an actual problem of rating of peculiarities of decision making system by inexperienced and experienced doctors. There was developed a scale of peculiarities' evaluation of the system decision making, in which 5 factors associated with effective decision making such as informational, procedural/cognitive, emotional - volitional, motivational and communication are distinguished. The results of investigation according to scale rating revealed significant differences by some factors in the tested groups

Detailed description and justification of the maxillofacial markers of chronic alcoholism was done. There were shown the prevalence of chronic inflammatory periodontal diseases and chronic periodontitis, which during the period of abstinence in the background of the deep decline of the antimicrobial immune defense have a tendency to aggravate. There were presented data on peculiarities of gusto-reception and salivation in patients with alcohol dependence. It was proved the influence of substance abuse on the morphofunctional lingual status. To facilitate the identification of alcohol-depended pathology in providing dental care at the outpatient reception, a formalized map, unifying the diagnostic process, was offered.

The purpose of the study is to determine the role of 5HT4-receptors in excitatory responses of the stomach to exogenous serotonin. Experiments were performed in 27 rats under surgical anesthesia, mechanical ventilation, bilateral vagotomy and bilateral transaction of the glossopharyngeal nerve. Gastric mechanical activity was recorded during serotonin adipate infusion to intact animals and on the background of the ongoing actions of cholinergic, adrenergic antagonists and S 39604-the blocker 5-HT4-receptors. Simultaneous blockade of adrenergic and cholinergic receptors did not prevent, but amplify stimulatory effect of serotonin. 5-Ht4 receptor blockades eliminate excitatory reactions. It was concluded that serotoninergic structures exerted their control influence by 5-HT4-receptors.

There were studied and summarized results of theoretical and practical works of domestic and foreign neurology centers and manufacturing firms, producing implanted systems for detection and prophylaxis of epileptiform activity. Special attention was paid to neuroingeneric aspects of building such systems, particularly the systems of joint fields: neurology, system technique, micro-and-nanoelectronics. Conception of development of original neuromodullar system was offered.

The review of literature and our own data on a role of a perinatal pathology of a brain, in particular of presented ischemia and hypoxia, in formation of a syndrome of deficiency of attention with hyperactivity were shown. Results of research have demonstrated, that the combination of ante- and intranatal factors appears to be defining in a parentage of the majority of аttention deficit and hyperactivity disorder cases. At the majority of children with аttention deficit and hyperactivity disorder signs of the transferred hydrocephaly or a patrimonial cervical trauma are noticed. Results of video-EEG-monitoring at patients with аttention deficit and hyperactivity disorder are reflected.

It was shown that improvement of diagnostic methods and pharmacological development in the recent years caused a significant progress in the sphere of medical help to the epileptic patients. But at the same time an active usage of antiepileptic drugs has not also increased curability of epilepsy, but has also raised the risk of drug-associated complications. Unfavorable adverse reactions of antiepileptic drugs substantially increase cost of therapy, defalcate patient's trust to a doctor and worsen patient's quality life. One of unfavorable adverse reactions is antiepileptic drugs' ability to provoke or aggregate epileptic seizures in some paradox way.

The incidence, prevalence and sex-age structure of Parkinson's disease according to the data of appealability to the Republican clinicodiagnostic centre of extrapyramidal pathology and botulinotherahy are presented in the article. Analysis of etiology of secondary Parkinsonism and Parkinsonian syndrome causes of false diagnosis and ways of improving medical treatment quality for patients with Parkinsonism in the Republic of Tatarstan were examined.

The article describes psychodynamic conception of "ascending balance" adaptability. Results of longitude research of mothers' adaptability in maturation process of children with infantile cerebral paralysis are presented. Classification of adaptability types and information about psychological aspect of genesis of personal changes are presented. Main types of manifestation of mothers' adaptability on different stages of children maturation depending on subjective relations, mental experience and motivational-semantic relations are analyzed.

The peculiarities of autonomic homeostasis according to spectral analysis of cardiac rhythm variability with an active orthostatic test in 191 patients with vegetative crises of a light, middle and heavy degree of severity and with different disease duration have been revealed. Being the highly informative method, the heart rate variability should be recommended as an essential diagnostic test for detecting vegetative disorders.