ASTROCYTES AND SYNAPTIC PLASTICITY. PART II. EXTRACELLULAR MATRIX AND PERINUERONAL NET

Abstract

Here we present modern data on astrocyte participation in the formation of extracellular matrix (ECM) and its specialization in the perineurona nets (PNN) and significance of ECM/PNN in synaptogenesis and synaptic plasticity. Special attention was given to schizophrenia and ECM alterations as a critical mechanism in synaptic pathology in the schizophrenia.

Keywords

synapse / astrocytes / extracellular matrix / perineuronal nets

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RIGHTS & PERMISSIONS

Shvalev V.N., Sosunov A.A., Chelyshev Y.A.