NORMAL CONNECTIVE-TISSUE SKELETONOF THE PENIS AND ITS CHANGESIN PATIENTS WITH ERECTILE DYSFUNCTIONAND PEYRONIE'S DISEASE

A I Neymark; V V Klimachev; V Ya Gerval'd; I P Bobrov; A M Avdalyan; H I Muzalevskaya; I V Gerval'd; P T Aliev; M A Kazymov; A I Neimark; V V Klimachev; V Ya Gervald; I P Bobrov; A M Avdalyan; N I Muzalevskaya; I V Gervald; R T Aliyev; M A Kazymov

doi:10.17816/morph.399222

Morphology ›› 2009, Vol. 136 ›› Issue (6) : 75 -78. DOI: 10.17816/morph.399222

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NORMAL CONNECTIVE-TISSUE SKELETONOF THE PENIS AND ITS CHANGESIN PATIENTS WITH ERECTILE DYSFUNCTIONAND PEYRONIE'S DISEASE

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Altai State Medical University

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Abstract

The aim of this study was to examine the connective tissue of penis in normal individuals and in patients with erectile dysfunction(ED) and Peyronie's disease (PD) using computer methodsof image analysis. Penis tissues were obtained from 20 malesaged 20-40 years who died in accidents, penis biopsies weretaken from 23 patients with ED and 9 patients with PD (averageage: 51±11,5 years). In both groups of patients, the volumetricfraction of collagen fibers in the tunica albuginea and corporacavernosa was increased, while that one of elastic fibers was decreased.At the same time, the changes of elastic fibers were noted: the fibers become thinner and formed rods. The reduction of the amplitude and the wavelength in the collagen fibers of the tunicaalbuginea in patients with ED and the presence of fibrous plaquesin corpora cavernosa in in patients with PD were registered. The methods of computer image analysis may improve the morphologicdiagnosis of ED and PD.

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penis / connective-tissue skeleton / erectile dysfunction / Peyronie's disease

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A I Neymark, V V Klimachev, V Ya Gerval'd, I P Bobrov, A M Avdalyan, H I Muzalevskaya, I V Gerval'd, P T Aliev, M A Kazymov, A I Neimark, V V Klimachev, V Ya Gervald, I P Bobrov, A M Avdalyan, N I Muzalevskaya, I V Gervald, R T Aliyev, M A Kazymov. NORMAL CONNECTIVE-TISSUE SKELETONOF THE PENIS AND ITS CHANGESIN PATIENTS WITH ERECTILE DYSFUNCTIONAND PEYRONIE'S DISEASE. Morphology, 2009, 136(6): 75-78 DOI:10.17816/morph.399222

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