In 1896 at the All-Russian Exhibition in Nizhny-Novgorod, in the department of the Kazan firm br. Krestovnikovs, one fat-like substance was exhibited under the name "Lipogenin", intended for use in medicine. among local doctors, who used it as a perceiving medium for ointments.

Before talking about atrophic cirrhosis of the liver with a large spleen, we consider it necessary to dwell in some detail on cirrhosis of the liver in general. At the seventh congress of the society of Russian doctors in memory of N.I. Pirogov in 1899 in Kazan, the late prof. pathological anatomy NM Lyubimov made a report on the topic "On the classification of cirrhosis of the liver" on the basis of modern scientific medicine.

In October 1909, the speaker met at an autopsy a completely peculiar liver damage in a 21-year-old child, more than 3 years of diarrhea and a significant increase in the spleen (with ascites); the last one was removed to him, and the patient died from septic peritonitis. The liver was smooth, 1270 gm. vѣsom and extremely soft; in the portal vein and she herself turned out to be clogged with blood clots, red — in the liver, and whitish — in the drink itself. Liver tissue appeared to be red and och. soft, in some places whitish-yellowish color; areas of the last days formed nodes in the forms of cerebral convolutions, enveloping the rays of the Glisson capsule with large veins; the convolutions seemed striated, as if folded from the tubes, vertical to the axis of the crossbeam of the Glisson capsule. Such whitish areas were scattered everywhere and in the red parenchyma, not sharply delimited * from it and without lobular structure.

Protocol of the appointment of the Society of Physicians at the Imperial Kazan University
17th November 1909
It was chaired by prof. N.A. Gerken under the secretary of Dr. A. V. Favorskom.

Protocol of the appointment of the Society of Physicians at the Imperial Kazan University
November 25, 1909
Action. Member of the Island AA Desyatov sent a message: "On the city health care in Kazan."

Protocol of the appointment of the Society of Physicians at the Imperial Kazan University
December 22, 1909
Pervushin was chaired by the secretary Dr. Shibkov.

Protocol of the appointment of the Society of Physicians at the Imperial Kazan University
7th November 1909
Chaired by Comrade Chairman V.P. Pervushin with Secretary Dr. A. V. Favorskom.

Protocol of the appointment of the Society of Physicians at the Imperial Kazan University
December 16th.
It was chaired by prof. N.A. Gerken under the secretary of Dr. A. V. Favorskom.