Scientific session of the Cardiological Scientific Center of the Russian Academy of Medical Sciences "Emergencies in Cardiology" (Moscow, January 20-21, 1994)

Abstract

Various aspects of the problem were discussed at the plenary and breakout sessions, as well as at the round table. Prof. M. Ya. Ruda (Moscow) in his report “Modern approaches to the treatment of acute myocardial infarction” noted that restoration of coronary blood flow is the key to successful treatment of the disease. Pointing out that myocardial necrosis begins 30 minutes after the occlusion of the coronary artery, after 2 hours 50% of the affected area "dies", and after 4 hours - all 100%, he stressed that from these positions, after 4 hours from the onset of the disease, thrombolytic therapy already ineffective. Therefore, it should be started at the prehospital stage. The most widely used tissue plasminogen activator and, especially, streptase (ST), with the use of which less often develop retrombosis and cerebral strokes. In addition, the CT is cheaper. In the prevention of retrombosis, aspirin, heparin can be useful (5000 units intravenously, then infusion of 1000 units per hour for 2 days under the control of blood clotting time). Prof. M. Ya. Ruda also said that at present, the administration of magnesium salts is widely used abroad in the acute period of myocardial infarction, which significantly reduces mortality. Perhaps, he added, "they will soon start with magnesium salts."

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