Treatment of typhoid fever by administration of vaccine per os. Alisov and Morozkin (Russ. Klin., 1927, Oct.)
B. Agricolansky
Kazan medical journal ›› 1928, Vol. 24 ›› Issue (4) : 474 -474.
Treatment of typhoid fever by administration of vaccine per os. Alisov and Morozkin (Russ. Klin., 1927, Oct.)
Having used treatment with a heat-killed vaccine in a number of typhoid diseases, the authors arrived at the following results: 1) per os vaccine therapy in 46% of cases produces a cut-off therapeutic effect; in 38% of cases it saves strength of the patient by reducing the duration of the disease, decreasing t° and eliminating intoxication, thus promoting rapid recovery and preventing development of complications; it reduces mortality rate almost fourfold; 2) to obtain a clear therapeutic effect it is necessary to apply doses of 50-100 billion bacterial bodies per day for at least 4-5 days on an empty stomach, preferably after prior sensitization of the intestine laxative (10.0-12.0 magnesium sulfate).
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