Phagocytic reactions of inflammation in the clinic and pathogenesis of rheumatoid arthritis
I. G. Salikhov
Kazan medical journal ›› 1994, Vol. 75 ›› Issue (3) : 197 -199.
Phagocytic reactions of inflammation in the clinic and pathogenesis of rheumatoid arthritis
The inflammation underlying rheumatoid arthritis (RA), being a multicomponent and multi-stage process, essentially determines the clinical polymorphism of the disease. The analysis of the literature data on the functional state of neutrophils as effector cells of rheumatoid inflammation, on the participation of polymorphonuclear leukocytes in the formation of the clinical picture of the disease is difficult: they are few, contradictory and rarely contain conclusions of applied significance. There is no consensus on the nature of chemotactic, phagocytic and bactericidal functions of neutrophils. In addition, the functional state of blood neutrophils, synovial fluid and related phenomena is currently an insufficiently studied aspect of the pathogenesis and clinic of rheumatoid arthritis.
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