On Friedberger's and Reis's reaction in typhus
M. R. Borok , A. I. Mirkin
Kazan medical journal ›› 1923, Vol. 19 ›› Issue (1) : 24 -31.
On Friedberger's and Reis's reaction in typhus
In searching for evidence in favor of the etiological significance of b. proteus vulgaris x19 in typhus and on the assumption that typhus patients must be hypersensitive to this microbe, Prof. Friedberger together with Dr. Reis in 1919 applied subcutaneous (and also intradermal) administration to typhus patients of suspensions of killed bacilli of b. prot. prot. vulgaris x19. Friedberger and Reis expected that when certain doses of this suspension, which were completely indifferent to healthy persons, were administered, typhus patients would react to them in the same manner as, for example, tuberculosis patients react to tuberculin injections.
Borok M.R., Mirkin A.I.
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