On the toxicity of methylene blue

A. I. Puchek

Kazan medical journal ›› 1927, Vol. 23 ›› Issue (11) : 1091 -1097.

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Kazan medical journal ›› 1927, Vol. 23 ›› Issue (11) : 1091 -1097. DOI: 10.17816/kazmj77566
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On the toxicity of methylene blue

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Abstract

Methylene blue was discovered by the chemist Careau at the end of the 19th century. R. Koch, in 1882, first used it in microscopic technique, working with the tuberculosis pathogen he had discovered. Later, in 1890, Ehrlich noticed the affinity of methylene blue for nerve tissue and its analgesic effect. A year later it was suggested by Gutmann, and then by Giems for treatment of malaria. Since that time, blue has been used for the treatment of a wide variety of diseases and, as can be seen from the literature, with some success, for example, in diseases of the urinary tract of a gonorrheic nature, in dysentery, recurrent typhus, in tuberculosis of the throat, in neoplasms, nephritis of an infectious nature, etc.

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A. I. Puchek. On the toxicity of methylene blue. Kazan medical journal, 1927, 23(11): 1091-1097 DOI:10.17816/kazmj77566

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