The way through liquor. A. Hauptmаnn (Zeit. f. d. ges. Neur. u. Psych., Bd. 102)
M. Andreev
Kazan medical journal ›› 1927, Vol. 23 ›› Issue (6-7) : 748 -748.
Analyzing clinical and experimental data of different authors, Hauptmann comes to the following conclusions: metalytic diseases cannot be explained only by the presence of spirochaetes in the brain; of great importance here are also the general toxic effects of the luetic infection; Whereas the immune-strong organism destroys the spirochaetes by phagocytosis (hence the strong secondary reactions), the immune-weak one (future metalyuetes, without strong cutaneous reactions) fights them extracellularly as with any foreign protein; this weakness may depend on the organism itself and on the spirochaetes (e.g. , The endotoxins released during the second kind of struggle affect especially the vascular endothelium and increase the permeability of the "barrier between the blood and the liquor".
Andreev M.
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