Influence of ultraviolet irradiation on the therapeutic activity of sulfonamides in patients with chronic pneumonia

S. A. Matveeva

Kazan medical journal ›› 1980, Vol. 61 ›› Issue (4) : 10 -13.

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Kazan medical journal ›› 1980, Vol. 61 ›› Issue (4) : 10 -13. DOI: 10.17816/kazmj64141
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Influence of ultraviolet irradiation on the therapeutic activity of sulfonamides in patients with chronic pneumonia

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Abstract

In a comparative aspect, the pharmacokinetics and clinical efficacy of sulfonamides (sulfadimezine and sulfamonomethoxin) were studied in their treatment of patients with chronic pneumonia with and without UV irradiation. It has been shown that the course use of sulfonamides with UV irradiation leads to an increase in the content of their total and free forms, their acetylation in the blood, and an increase in the total acetylating ability of the organism. The combined use of sulfonamides with UV irradiation is clinically more effective.

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S. A. Matveeva. Influence of ultraviolet irradiation on the therapeutic activity of sulfonamides in patients with chronic pneumonia. Kazan medical journal, 1980, 61(4): 10-13 DOI:10.17816/kazmj64141

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