Dynamics of the concentration of immunoreactive insulin and growth hormone in the blood of patients with acute viral hepatitis

Abstract

During a test for glucose tolerance in 40 patients with acute hepatitis, the dynamics of glycemia and the content of immunoreactive insulin in the blood was studied, and in 22 of them, along with this, the concentration of growth hormone in the blood serum. Disorders of glucose tolerance were revealed in 20 patients with acute viral hepatitis. The amount of glucose and immunoreactive insulin in the blood after taking glucose in these patients was significantly higher than in healthy people. The content of growth hormone in blood serum on an empty stomach and after glucose intake is also increased. In patients with acute viral hepatitis, the level of glycemia was slightly higher, and the level of immunoreactive insulin was slightly lower than in patients with chronic hepatitis. The concentration of growth hormone in the blood of patients in these 2 groups did not differ significantly. The disorders registered in the acute period of viral hepatitis were completely eliminated 1.5 years after recovery. This allows us to conclude that the revealed changes are based on liver disease.

References

[1] Кулиев М. А. Ученые записки Азербайджанского ГИДУВа. 1967, 8

[2] Лейбуш Б. Н. Инсулиновая активность крови при остром эпидемическом гепатите. Автореф. канд. дисс., Л., 1966

[3] Adi F. С. Brit. Med. J., 1974, 1, 5900.

[4] DonowskiT., Gillespie H. a. о. J. biol. Med., 1956, 29. 361.

[5] Hall K. Acta Endocrinol., 1972, Suppl. 163, 1.

[6] Lang S., Goldstein M.,Levine R. Am. J. Physiol., 1954, 1977, 447.

[7] Nieschlag E., Kremer G., M u s t i g U. Klin. Wschr., 1970, 48, 6.

[8] Wu A., Grant D. a. o. Clin. Sei., 1974, 47, 4

RIGHTS & PERMISSIONS

Miroshnichenko A.G., Shlimovich P.B., Gnevasheva G.I.