A comprehensive assessment of hemodynamics of blood vessels, lower leg in patients at different times, the late period of deformative arthrosis of the ankle joint (DAGS) according to the gravity, which allows to predict its course, outcomes and identify the occurrence of complications were carried out. Dynamic monitoring of patients contributed to the high efficiency of the differentiated approach to the management of each category of patients in the long term DAGS was made. The authors have obtained information that the outcome depends on the violation of vascular autoregulation leg hemodynamics in different periods of deforming arthrosis of the ankle joint of any severity. Identified data provide an opportunity to optimize a differentiated approach in the treatment of patients with distant periods of follow-up monitoring.

The performed analysis of the morphology of cardiomyocytes and myocardial vascular bed in 12 pregnant rats and 16 newborn pups exposed to the hemic hypoxia induced by NaNO 2 revealed some similar degenerative and destructive changes which were more pronounced in pups. The main morphological characteristics of hypoxic myocardial damage in pregnant and newborn rats were presented in the form of phenomena of mixed dystrophy, swelling and destruction of endothelial cells and contractile cardiomyocytes along with the lysis of myofibrils, perivascular edema, capillary hyperemia, emptiness and spasm of the arterioles and contracture changes. Revealed pathological changes in the myocardium reflect the development of the myocardiodystrophy processes in pregnant rats and newborn pups.

The changes in the parameters of the corpus callosum, depending on the type of flow, duration of disease and degree disability in multiple saclerosis. Most sensitive with respect to the investigated indices proved trunk of the corpus callosum, to a lesser extent the knee. For the same period of the disease atrophy of the corpus callosum in patients with primary progressive course of multiple sclerosis is much more pronounced than in other types of flow. Reducing the size of the corpus callosum in progressive types of flow suggests ongoing secondary degeneration of fibers.

The complex analysis of indications to cesarean delivery in the Ryazan Regional Clinical Perinatal Center during 2011-2013 is carried out. Frequency of cesarean delivery was 32.8%. Earlier undergone surgeries on a uterus made 26,4% in structure of all indications to cesarean delivery. Results of research showed that conservative conducting childbirth at pregnant women after the undergone surgeries on a uterus is an essential reserve of decrease in number of cesarean delivery. The main conditions of conservative conducting childbirth: anatomic and functional quality of a uterus; clinical compliance of the sizes of a fetus and woman's pelvis; absence of absolute contraindications to childbirth from mother and fetus.

The article provides information about the topography and morphology of the parathyroid gland depending on sex, age and ethno-territorial somatotypological features. Establishing of relations between shapes, sizes with topography and morphological parameters of parathyroid gland allow to predict the location of the parathyroid gland before operation, and therefore to optimize the performance of operations on the thyroid and parathyroid glands.

Modern demographic situation determines the need for optimization of organizational technologies in nursing regional maternity hospitals, which will allow more efficient distribution and use of human resources, to co-ordinate services and facilities to meet the requirements of the current situation.

Determined the chemical composition of the main tree species, understory and ground cover of pine plant communities Meshchera. These areas belong to the National Park and area natural geochemical sample "background", because quite removed from sources of industrial pollution. However, the pine forest biogeocenoses formed on mineralogiccally a poor substrate, under conditions of pronounced deficit of nutrients. In these conditions, a large role is played by the position of phytocenoses in the microrelief and the groundwater level. The features of the absorption and accumulation by plants of calcium, magnesium, iron, manganese, zinc and copper. Revealed a pronounced deficiency of calcium, magnesium and copper in coniferous species with a relative accumulation of vegetation iron and manganese. It is established that intensive extraction of chemical elements from the soil and rapid treatment in the plant-soil system ensures the stable operation of biogeocenoses pine forests with initially low availability of nutrients.

In the conditions of educational process in secondary schools evaluated the types of vegetative regulation pupils with complex "Varikard 2.51" before and after the lesson of physical culture. Given a certain type of vegetative regulation of schoolchildren and correcting physical activity, warned dysregulatory manifestations of the body of pupils.

The authors analyze the remote results of the treatment of 345 patients with Graves disease in this article. Principal reasons which determine thyroid status of patients after surgery in the nearest and remote observation period. The technique to eliminate the recurrence of Graves’ disease. For example, 26 patients shown the way and the results of the alternative treatment of relapse of Graves’ disease, by percutaneous 96% alcohol sclerotherapy in the hospital. As a result, 15 (57,7%) patients achieved a euthyroid state, in 3 patients (11,5 %) this method was ineffective.

Lower infant mortality rates, which is an important component of mortality of children under 14 years were noted in the Samara region 2004 to 2011 compared to the Volga Federal District and the Russian Federation. It was stated that the reduction in mortality of children in the age group of 1 to 4 years due to the decrease in its rates from malignancies, congenital malformations and external causes. Measures to improve the health of children and adolescents implemented within the framework of regional target programs and projects are also considered in the article.

The comprehensive study on the prevalence of risk factors for malignant neoplasms of the larynx among the population was done. The screening test was proposed and a mathematical-statistical model to determine the probability of individual risk of larynx cancer was created. "The methodology of forming high-risk groups in the incidence of malignant neoplasms of the larynx and organization of the dispensary supervision" was done, which allows to improve the quality of the preventive and clinical work with the population.

In the article the complex analysis of indices of mental health in population of Ryazan region for 2003-2013 years has been presented. The tendencies of changes of statistic data in the region as compared to the information around Russia has been estimated. Negative tendencies of population’s mental health indices, decrease of primary detection of mental disorders have been found.

The study of anthropometric parameters and indexes in groups, formed according to the canon of proportionality, was carried out. Three groups were formed, which differed significantly from each other. In most of 68,5% of the examined students the ontogenetic maturation was completed. In 31,5% of girls, whose arm span exceeded growth, the proportions are able to be changed under the influence of external and internal factors. A simple and affordable approach, proposed by us, allows to carry out the screening of body harmony and to estimate the completion of the growth processes.

The article presents the ultrastructural features of utero-placental area in early pregnancy with urogenital infection. The description of the ultrastructural changes in syncytiotrophoblast, decidual cells, multinucleated giant cells, blood vessels of the microvasculature.

Experimental facts of this article show, that the soluble polysaccharide complex of Amelanchier Medic (Amelanchier vulgaris) induces erythropoesis by increasing the level of erythrocytes and hemoglobin in blood of experimental rats and changes the level of lymphocytes, leucocytes and monocytes. The following changes occur in blood of the experimental animals: increase in the level of iron and iron-binding properties of serum as well as a change in the level of protein fractions. Polysaccharide of Amelanchier Medic (Amelanchier vulgaris) causes increase in the mass of spleen and decrease in the mass of thymus increases of physical activity of experimental animals.

The paper presents an analysis of the existing national legislation regulating relations in the part of the processing of personal data in the activities of medical institutions - the Federal Law «On personal data» of 27.07.2006 № 152-FZ, Federal Law «On Compulsory Health Insurance in the Russion Federation» dated 29.11.2010 № 326-FZ and the Federal Law of the Russion Federation» «On the basis of health protection in the Russion Federation» dated 21.11.2011 № 323-FZ.

The paper presents the results of a study of health and demographic indicators, indicating the priority of air pollution populated areas of road transport emissions, a key factor in the environment, have a negative impact on the health of the child population. The necessity of the development and implementation of measures aimed at reducing air pollution of the city.

The article from the late 19th century to the present days analyzed the history of dental care of Ryazan region and the emergence of the first dental clinics. History of formation of dental care in the Ryazan region show great work of dentists in improving the provision of medical care at all stages of development of health care of the Russian Federation.

In article from hygienic and ecological positions the review of material on a problem of ecologically caused incidence in interrelation with processes of change of environment is stated. Modern approach to a problem environment - health of the person which main shortcoming is absence of the accounting of prevalence of the prepathological states having the criteria and predictive importance is sounded. It is emphasized that today there are no bases to denial of ecological incidence, and it should be revealed in the general stream of diseases. Allocation of "ecological medicine" as the independent scientific and practical direction is necessary and to realize official statistics with registration of ecologically reasonable incidence in relation to the international classification of diseases.

White adipose tissue (WAT) distribution (visceral fat predomination) and amount (adipose cell hypertrophy) may be a crucial risk factor of metabolic disorders. Present study shows effects of aerobic and anaerobic exercises on morphometric characteristics of mesenteric and subcutaneous WAT in hi-fat diet induced obese rats. The study found that animals, received hi-fat diet, demonstrate prevalence of small-size adipocytes. Probably it protects ectopic tissues from lipotoxic effects. Anaerobic physical exercises reduce amount of mesenteric WAT in normal rats received standard chow. Applied with hi-fat diet, anaerobic physical exercises reduce amount and size of fat cells in mesenteric WAT, but aerobic physical exercises reduce the same characteristics in subcutaneous WAT.

Fetal brain was retrospectively evaluated in normal fetuses at 16-27 weeks of gestation, obtained by multiplanar echography. In axial cerebral plane was measured transverse cerebellar diameter. All measurements were done from as the widest diameter across both hemispheres in an outer-to outer fashion. In mid-sagittal plane was measured craniocaudal diameter and anteroposterior diameter of the cerebellar vermis. Craniocaudal diameter was defined as maximum distance between cranial and caudal surfaces of the vermis, anteroposterior diameter was defined as the maximum distance between anterior and posterior surfaces of the vermis. Normal range plotted on the reference range of the transverse cerebellar diameter, craniocaudal diameter and anteroposterior diameter of the cerebellar vermis. Measuring of its size may be useful for comprehensive ultrasound assessment of the fetal cerebellum in the second trimester of pregnancy.

The present article deals with the results of the investigation of clinical and psychological characteristics of 70 patients with endometrial cancer, which have had a hysterectomy. The comparison group consisted of 70 women with uterine myoma which had also been operated (amputation). Patients had been investigated before and after the surgery. The most patients with endometrial cancer had anxious type of reaction to the disease, the greatneed for independence and communication need. The received data can be used for psychotherapeutic treatment.

In operation, on the basis of a study of 76 cases of endometrioid ovarian cancer shows a significant role of quantitative and qualitative changes of nucleic acids in tumor cells, which are associated with increased likelihood of developing metastases. Also indicated on the role and importance of photometric and ploidometric diagnosis of uveal melanomas research in the practice of medical Oncology profile for the subsequent plan treatment of patients and the prognosis of the disease.

Polysaccharide complex extracted from tansy (Tanacetum vulgare L.) flowers is pectines type glucuronolactone. Its hepatoprotective activity was assessed on the model of acute toxic hepatitis caused by introduction of carbon tetrachloride 50% solution. It was found that the polysaccharide reduced the asparte aminotransferase activity, decreases the level of malondialdehyde, increases the amount of free SH-groups and glutathiontransferase activity in lysate of erythrocytes, i.e. polysaccharide complex has a pronounced hepatoprotective and antioxidant properties.