Diagnosis and treatment of male infertility in patients with common pathology of genitals and inguinal region
I. S. Sobennikov , B. N. Zhiborev , S. Ya. Kotans , A. A. Cherenkov
I.P. Pavlov Russian Medical Biological Herald ›› 2017, Vol. 25 ›› Issue (3) : 460 -468.
Diagnosis and treatment of male infertility in patients with common pathology of genitals and inguinal region
The article presents a study of reproductive function and fertility prognosis in 27 male patients of reproductive age with common diseases of genitals and inguinal region. These patients were under observation in the outpatient clinics with the diagnosis of male infertility. Blood levels of sex hormones and spermograms were evaluated in dynamics before and after surgical treatment of the main disease. In the research it was found that surgical removal of the probable cause of infertility in marriage resulted in normalization of spermogram parameters in 15% of cases and to the onset of pregnancy in 22.2% of cases. No significant changes in the dynamics of sex hormones were found. Besides, in the course of research a positive clinical effect of conservative treatment for the connective tissue dysplasia associated with the main disease and infertility in marriage, was obtained. This effect was confirmed by the onset of pregnancy in 29.4% of patients who underwent drug therapy.
inguinal hernia / varicocele / connective tissue dysplasia / infertility
| [1] |
1.Gamidov SI, Iremashvili VV, Tha-gapsoeva RA. Muzhskoe besplodie: sovre-mennoe sostoyanie problemy [Male infertility: the current state of the problem]. Farmateka [Pharmateka]. 2009; 9: 12-7. (in Russian) |
| [2] |
1.Гамидов С.И., Иремашвили В.В., Тхагапсоева Р.А. Мужское бесплодие: современное состояние проблемы // Фарматека. 2009. №9. С. 12-17. |
| [3] |
2.Stepanov VN, Kadyrov Z.A. Diag-nostika i lechenie varikocele [Diagnosis and treatment varikotsele]. Moscow: Trasdor-nauka; 2001. 11 p. (in Russian) |
| [4] |
2.Степанов В.Н., Кадыров З.А. Диагностика и лечение варикоцеле. Моск¬ва: Трасдорнаука, 2001. 11 с. |
| [5] |
3.Akramov NR Omarov TI, Gima-deeva LR, Gallyamova AI. Reproduktivnyj status muzhchin posle klassicheskoj gernioplastiki, vypolnen-noj v detskom vozraste pri pahovoj gryzhe [Reproductive status of men after classical hernioplasty performed in childhood with inguinal hernia]. Kazanskij medicinskij zhurnal [Kazan Medical Journal]. 2014; 95 (1): 7-11. (in Russian) |
| [6] |
3.Акрамов Н.Р., Омаров Т.И., Гима-деева Л.Р., Галлямова А.И. Репродуктивный статус мужчин после классической гернио-пластики, выполненной в детском возрасте при паховой грыже // Казанский медицин-ский журнал. 2014. Т. 95, №1. С. 7-11. |
| [7] |
4.Yamaguchi K, Ishikawa T, Nakano Y, Kondo Y, Shiotani M, Fujisawa M. Rapidly progressing, late-onset obstructive azo-ospermia linked to herniorrhaphy with mesh. Fertil. Steril. 2008; 5: 5-7. |
| [8] |
4.Yamaguchi K., Ishikawa T., Nakano Y., Kondo Y., Shiotani M., Fujisawa M. Rapidly progressing, late-onset obstructive azoospermia linked to herniorrhaphy with mesh // Fertil. Steril. 2008. № 5. P. 5-7. |
| [9] |
5.Kirillov YuB, Astrakhantsev AF, Zotov IV. Morfologicheskie izmeneniya yaichka pri pahovyh gryzhah [Morphological changes in the testicle during inguinal hernia]. Hirurgiya [Surgery]. 2003; 2: 65-7. (in Russian) |
| [10] |
5.Кириллов Ю.Б., Астраханцев А.Ф., Зотов И.В. Морфологические изменения яичка при паховых грыжах // Хирургия. 2003. №2. С. 65-67. |
| [11] |
6.Zhiborev BN. Hirurgicheskie zabo-levaniya polovoj sistemy muzhchin i naru-sheniya fertil'nosti [Surgical diseases of the reproductive system of men and impairment of fertility]: dis. doct. (Med. Sci.). Ryazan; 2008. (in Russian) |
| [12] |
6.Жиборев Б.Н. Хирургические заболевания половой системы мужчин и нарушения фертильности: автореф. дис. ... д-ра мед. наук. Рязань, 2008. 50 с. |
| [13] |
7.Yakovlev VM, Nechaeva GI. Klassi-fikacionnaya koncepciya nasledstvennoj dis-plazii soedinitel'noj tkani [Classification conception of hereditary connective tissue dysplasia]. Omskij nauchnyj vestnik [Omsk scientific herald]. 2001; 16: 68-70. (in Russian) |
| [14] |
7.Яковлев В.М., Нечаева Г.И. Клас-сификационная концепция наследственной дисплазии соединительной ткани // Омский научный вестник. 2001. №16. С. 68-70. |
| [15] |
8.Mosca M. Mixed connective tissue diseases: new aspects of clinical picture, prognosis and pathogenesis. Isr. Med. Assoc. J. 2014; 16 (11): 725-6. |
| [16] |
8.Mosca M. Mixed connective tissue diseases: new aspects of clinical picture, prognosis and pathogenesis // Isr. Med. Assoc. J. 2014. Vol. 16, №11. P. 725-726. |
| [17] |
9.Bannikov G.A. Molekulyarnye mekhanizmy morfogeneza [Molecular mechanisms of morphogenesis]. In: Results of science and technology. VNIITI and morphology of humans and animals. M., 1990. Vol. 14. 148 p. (in Russian) |
| [18] |
9.Банников Г.А. Молекулярные механизмы морфогенеза // Итоги науки и техники. ВНИИТИ и морфология человека и животных. М., 1990. Т. 14. 148 с. |
| [19] |
10.Kadurina TI, Gorbunov VN. Displaziya soedinitel'noj tkani [Connective tissue dysplasia: manual for doctors]. St. Petersburg: Elbi-SPb; 2009. 704 p. (in Russian) |
| [20] |
10.Кадурина Т.И., Горбунова В.Н. Дисплазия соединительной ткани: руко-водство для врачей. СПб.: Элби-СПб, 2009. 704 с. |
| [21] |
11.Tvorogova TM, Vorobyova A.S. Nedifferencirovannaya displaziya soedinitel'-noj tkani s pozicii dizehlemen-toza u detej i podrostkov [Undifferentiated connective tissue dysplasia from the perspective of diselementosis in children and adolescents]. RMZH [RMJ]. 2012; 24: 12-5. (in Russian) |
| [22] |
11.Творогова Т.М., Воробьева А.С. Недифференцированная дисплазия соеди-нительной ткани с позиции дизэлементоза у детей и подростков // РМЖ. 2012. №24. C. 12-15. |
| [23] |
12.Repina NB, Salha M. Ben Aktual'-nost' problemy spaechnogo processa v malom tazu, ego posledstviya i rol' nedifferenciro-vannoj displazii soedinitel'noj tkani v ego razvitii [The urgency of the problem of adhesions in the pelvis, its consequences and the role of undifferentiated connective tissue dysplasia in its development]. Rossijskij mediko-biologicheskij vestnik imeni akademika I.P. Pavlov [I.P. Pavlov Russian Medical Biological Herald]. 2016; 24 (1): 155-60. (in Russian) |
| [24] |
12.Репина Н.Б., Салха М.Бен Актуальность проблемы спаечного про-цесса в малом тазу, его последствия и роль недифференцированной дисплазии соеди-нительной ткани в его развитии // Россий-ский медико-биологический вестник име-ни академика И.П. Павлова. 2016. Т. 24, №1. С.155-160. |
Sobennikov I.S., Zhiborev B.N., Kotans S.Y., Cherenkov A.A.
/
| 〈 |
|
〉 |