IPL-therapy in ophthalmology: literature review

Rozaliya V. Gaybaryan , Yuriy B. Fedoseyev , Eric V. Vardanyan , Bella V. Vardanyan

I.P. Pavlov Russian Medical Biological Herald ›› 2025, Vol. 33 ›› Issue (1) : 117 -122.

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I.P. Pavlov Russian Medical Biological Herald ›› 2025, Vol. 33 ›› Issue (1) : 117 -122. DOI: 10.17816/PAVLOVJ501747
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IPL-therapy in ophthalmology: literature review

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Abstract

INTRODUCTION: In the modern world, the prevalence of ophthalmological diseases is steadily growing and remains a pressing problem today. Various congenital anomalies of the lacrimal glands, contaminated environment, unbalanced nutrition, taking various medical drugs, wearing contact lenses, irrational use of digital/electronic devices are provoking factors in the development of eye pathology. Chronic processes of the eyelids, such as dry eye syndrome, dysfunction of meibomian glands, blepharitis, blepharoconjunctivitis, recurrent chalazions, significantly reduce the quality of life and working capacity of patients. Disorder in stability of the tear film entails a cascade of pathological alterations. Conservative therapy — artificial tears, thermal applications, anti-inflammatory drugs, antiseptics, antibiotics are unable to provide complete long-term elimination of objective and subjective symptoms. One latest achievement in ophthalmology for these conditions is the use of intense pulsed light (IPL) therapy.

AIM: To analyze domestic and foreign literature sources on the use of IPL-therapy in ophthalmology, to determine the mechanism of its action, effectiveness of this treatment method, its advantages and disadvantages, as well as the possibility to use it for various eye pathologies.

The review summarizes the clinical results of the use of IPL-therapy in ophthalmology, discusses the possibilities of its incorporation in the algorithm of complex treatment of some ophthalmological diseases.

CONCLUSION: IPL-therapy is an effective and safe procedure in some chronic diseases of the anterior segment of the eye.

Keywords

IPL-therapy / intense pulsed light / dry eye syndrome / meibomian gland dysfunction / blepharitis

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Rozaliya V. Gaybaryan, Yuriy B. Fedoseyev, Eric V. Vardanyan, Bella V. Vardanyan. IPL-therapy in ophthalmology: literature review. I.P. Pavlov Russian Medical Biological Herald, 2025, 33(1): 117-122 DOI:10.17816/PAVLOVJ501747

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References

[1]

Toyos R, McGill W, Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; A 3-year retrospective study. Photomed Laser Surg. 2015;33(1):41–6. doi: 10.1089/pho.2014.3819

[2]

Toyos R., McGill W., Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; A 3-year retrospective study // Photomed. Laser Surg. 2015. Vol. 33, No. 1. P. 41–46. doi: 10.1089/pho.2014.3819

[3]

Loshkareva AO, Maychuk DY. Effectiveness of intense pulsed light in complex treatment of blepharitis and dry eye syndrome with meibomian gland dysfunction. Sovremennyye Tekhnologii v Oftal’mologii. 2019;(3):124–6. (In Russ). doi: 10.25276/2312-4911-2019-3-124-126

[4]

Лошкарева А.О., Майчук Д.Ю. Оценка эффективности применения методики интенсивного импульсного света в комплексном лечении блефаритов и синдрома «сухого глаза» с дисфункцией мейбомиевых желез // Современные технологии в офтальмологии. 2019. № 3. С. 124–126. doi: 10.25276/2312-4911-2019-3-124-126

[5]

Litvin I, Zumbulidze N, Parfenova M. Dry eye syndrome: «retribution» for progress. Vrach. 2022;33(7):77–81. (In Russ). doi: 10.29296/25877305-2022-07-16

[6]

Литвин И.Б., Зумбулидзе Н.Г., Парфёнова М.А. Синдром «сухого глаза»: «расплата» за прогресс // Врач. 2022. Т. 33, № 7. С. 77–81. doi: 10.29296/25877305-2022-07-16

[7]

Tashbayev B, Yazdani M, Arita R, et al. Intense pulsed light treatment in meibomian gland dysfunction: A concise review. Ocul Surf. 2020;18(4):583–94. doi: 10.1016/j.jtos.2020.06.002

[8]

Tashbayev B., Yazdani M., Arita R., et al. Intense pulsed light treatment in meibomian gland dysfunction: A concise review // Ocul. Surf. 2020. Vol. 18, No. 4. Р. 583–594. doi: 10.1016/j.jtos.2020.06.002

[9]

Vergés C, Salgado–Borges J, de Ribot FM. Prospective evaluation of a new intense pulsed light, thermaeye plus, in the treatment of dry eye disease due to meibomian gland dysfunction. J Optom. 2021;14(2):103–13. doi: 10.1016/j.optom.2020.08.009

[10]

Vergés C., Salgado–Borges J., de Ribot F.M. Prospective evaluation of a new intense pulsed light, thermaeye plus, in the treatment of dry eye disease due to meibomian gland dysfunction // J. Optom. 2021. Vol. 14, No. 2. P. 103–113. doi: 10.1016/j.optom.2020.08.009

[11]

Dell SJ. Intense pulsed light for evaporative dry eye dis ease. Clin Ophthalmol. 2017;11:1167–73. doi: 10.2147/opth.s139894

[12]

Dell S.J. Intense pulsed light for evaporative dry eye disease // Clin. Ophthalmol. 2017. Vol. 11. P. 1167–1173. doi: 10.2147/opth.s139894

[13]

Maychuk DYu, Loshkareva AO, Tsvetkova TV. The Complex Treatment Algorithm for Dry Eye Syndrome with Meibomian Gland Dysfunction. Combination of Intense Pulsed Light (IPL) with Eyelid Hygiene and Artificial Tears. Ophthalmology in Russia. 2020;17(3s):640–7. (In Russ). doi: 10.18008/1816-5095-2020-3S-640-647

[14]

Майчук Д.Ю., Лошкарева А.О., Цветкова Т.В. Алгоритм комплексной терапии синдрома сухого глаза с дисфункцией мейбомиевых желез интенсивным импульсным светом (IPL) в сочетании с гигиеной век и слезозамещением // Офтальмология. 2020. Т. 17, № 3s. С. 640–647. doi: 10.18008/1816-5095-2020-3S-640-647

[15]

Song Y, Yu S, He X, et al. Tear film interferometry assessment after intense pulsed light in dry eye disease: A randomized, single masked, sham-controlled study. Cont Lens Anterior Eye. 2022;45(4):101499. doi: 10.1016/j.clae.2021.101499

[16]

Song Y., Yu S., He X., et al. Tear film interferometry assessment after intense pulsed light in dry eye disease: A randomized, single masked, sham-controlled study // Cont. Lens Anterior Eye. 2022. Vol. 45, No. 4. P. 101499. doi: 10.1016/j.clae.2021.101499

[17]

Suwal A, Hao J–L, Zhou D–D, et al. Use of Intense Pulsed Light to Mitigate Meibomian Gland Dysfunction for Dry Eye Disease. Int J Med Sci. 2020;17(10):1385–92. doi: 10.7150/ijms.44288

[18]

Suwal A., Hao J.–L., Zhou D.–D., et al. Use of Intense Pulsed Light to Mitigate Meibomian Gland Dysfunction for Dry Eye Disease // Int. J. Med. Sci. 2020. Vol. 17, No. 10. P. 1385–1392. doi: 10.7150/ijms.44288

[19]

Leng X, Shi M, Liu X, et al. Intense pulsed light for meibomian gland dysfunction: a systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol. 2021;259(1):1–10. doi: 10.1007/s00417-020-04834-1

[20]

Leng X., Shi M., Liu X., et al. Intense pulsed light for meibomian gland dysfunction: a systematic review and meta-analysis // Graefes Arch. Clin. Exp. Ophthalmol. 2021. Vol. 259, No. 1. P. 1–10. doi: 10.1007/s00417-020-04834-1

[21]

Karaca EE, Evren Kemer Ö, Özek D. Intense Regulated Pulse Light for the Meibomian Gland Dysfunction. Eur J Ophthalmol. 2020;30(2):289–92. doi: 10.1177/1120672118817687

[22]

Karaca E.E., Evren Kemer Ö., Özek D. Intense Regulated Pulse Light for the Meibomian Gland Dysfunction // Eur. J. Ophthalmol. 2020. Vol. 30, No. 2. P. 289–292. doi: 10.1177/1120672118817687

[23]

Wladis EJ, Aakalu VK, Foster JA, et al. Intense Pulsed Light for Meibomian Gland Disease: A Report by the American Academy of Ophthalmology. Ophthalmology. 2020;127(9):1227–33. doi: 10.1016/j.ophtha.2020.03.009

[24]

Wladis E.J., Aakalu V.K., Foster J.A., et al. Intense Pulsed Light for Meibomian Gland Disease: A Report by the American Academy of Ophthalmology // Ophthalmology. 2020. Vol. 127, No. 9. P. 1227–1233. doi: 10.1016/j.ophtha.2020.03.009

[25]

Fishman HA, Periman LM, Shah AA. Real-Time Video Microscopy of In Vitro Demodex Death by Intense Pulsed Light. Photobiomodul Photomed Laser Surg. 2020;38(8):472–6. doi: 10.1089/photob.2019.4737

[26]

Fishman H.A., Periman L.M., Shah A.A. Real-Time Video Microscopy of In Vitro Demodex Death by Intense Pulsed Light // Photobiomodul. Photomed. Laser Surg. 2020. Vol. 38, No. 8. P. 472–476. doi: 10.1089/photob.2019.4737

[27]

Zhu Y, Huang X, Lin L, et al. Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalaziosis. Front Med (Lausanne). 2022;9:839908. doi: 10.3389/fmed.2022.839908

[28]

Zhu Y., Huang X., Lin L., et al. Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalaziosis // Front. Med. (Lausanne). 2022. Vol. 9. P. 839908. doi: 10.3389/fmed.2022.839908

[29]

Ruan F, Zang Y, Sella R, et al. Intense Pulsed Light Therapy with Optimal Pulse Technology as an Adjunct Therapy for Moderate to Severe Blepharitis-Associated Keratoconjunctivitis. J Ophthalmol. 2019;2019:3143469. doi: 10.1155/2019/3143469

[30]

Ruan F., Zang Y., Sella R., et al. Intense Pulsed Light Therapy with Optimal Pulse Technology as an Adjunct Therapy for Moderate to Severe Blepharitis-Associated Keratoconjunctivitis // J. Ophthalmol. 2019. Vol. 2019. P. 3143469. doi: 10.1155/2019/3143469

[31]

Gedar Totuk ÖM, Kabadayı K, Özkapı C, et al. Efficacy of Intense Pulsed Light Treatment for Moderate to Severe Acute Blepharitis or Blepharoconjunctivitis: A Retrospective Case Series. Turk J Ophthalmol. 2021;51(2):89–94. doi: 10.4274/tjo.galenos.2020.28924

[32]

Gedar Totuk Ö.M., Kabadayı K., Özkapı C., et al. Efficacy of Intense Pulsed Light Treatment for Moderate to Severe Acute Blepharitis or Blepharoconjunctivitis: A Retrospective Case Series // Turk. J. Ophthalmol. 2021. Vol. 51, No. 2. P. 89–94. doi: 10.4274/tjo.galenos.2020.28924

[33]

Li D, Lin S–B, Cheng L–H–H, et al. Intense Pulsed Light Treatment for Itch Associated with Allergic Keratoconjunctivitis: A Retrospective Study of 35 Cases. Photobiomodul Photomed Laser Surg. 2021;39(3):196–203. doi: 10.1089/photob.2020.4826

[34]

Li D., Lin S.–B., Cheng L.–H.–H., et al. Intense Pulsed Light Treatment for Itch Associated with Allergic Keratoconjunctivitis: A Retrospective Study of 35 Cases // Photobiomodul. Photomed. Laser Surg. 2021. Vol. 39, No. 3. P. 196–203. doi: 10.1089/photob.2020.4826

[35]

Toyos М, Toyos R, Jodoin B, et al. Results from a Prospective, Open-Label, Phase 4 Pilot Study of Repository Corticotropin Injection for Moderate and Severe Dry Eye Disease. Ophthalmol Ther. 2022;11(3):1231–40. doi: 10.1007/s40123-022-00501-2

[36]

Toyos М., Toyos R., Jodoin B., et al. Results from a Prospective, Open-Label, Phase 4 Pilot Study of Repository Corticotropin Injection for Moderate and Severe Dry Eye Disease // Ophthalmol. Ther. 2022. Vol. 11, No. 3. Р. 1231–1240. doi: 10.1007/s40123-022-00501-2

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