MYC FAMILY GENES IN SOLID-PSEUDOPAPILLARY TUMORS OF THE PANCREAS

Abstract

In the paper the study of molecular disorder genes c-Myc and N-Myc in solid-pseudopapillary tumor of the pancreas. Examined 24 samples of tumors obtained from 21 patients, including 19 primary, recurrent 1, 4 metastasis. Fluorescence in situ hybridization was performed using DNA samples lokusspetsificheskih to the loci 2p24, 6q23, 8q24 company «Vysis, Abbott Laboratories Inc», demonstrated that amplification of the N-Myc gene in solid-pseudopapillary tumor can be another confirming its neurogenic origin.

Keywords

the solid-pseudopapillary tumor of the pancreas / gene amplification / morphology / prognosis

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RIGHTS & PERMISSIONS

Gordienko E.N., Pakhlina O.V., Chekmareva I.A., Rothin D.L., Gorin D.S.