Clinical specific features of grippe-induced severe out-patient form of pneumonia

Abstract

The aim of the article is to study clinical specific features of grippe-induced severe out-patient form of pneumonia (OPP) using the comparative analyses of clinical, laboratory and x-ray examination data of severe out-patient form of pneumonia which was not connected with acute respiratory virus infection (ARVI). The first group included 25 patients (mean age - 35,6±2,8 years) with severe OPP induced by grippe. All patients were infected by grippe virus A/H1N1 swl. The second group consisting of 25 patients (mean age - 50,6±3,8 years) with severe OPP which was not associated with ARVI. Young and middle aged persons had grippe-induced OPP in whom the obesity of the II and III stages was the background disease of 28 % of patients. Fever (39,1 ºC or more) was marked in 60% of cases, the mean duration period of fever was 15,1±2,1 days. Stab neutrophil shift secondary or normal total amount of leucocytes was noted. 48% of cases showed the increase of transaminase level. It appeared that the lesion of two lobes of the lungs (76%) and bilateral damage of pulmonary tissue (72%) were characteristic signs. Complications in grippe-induced pneumonia occurred frequently. Acute respiratory distress syndrome (ARDS) was seen in 12% of cases.

Keywords

grippe-induced pneumonia / severe form of the disease / clinical picture / diagnosis

References

[1] Киселёв О.И., Ершов Ф.И., Сологуб Т.В., Романцов М.Г. (ред.) Грипп А/H1N1 как типичная эмерджентная инфекция (вирусологические, клинико-эпидемиологические особенности, вопросы терапии и профилактики): Пособие для врачей. Спб.; Харьков; Ужгород; 2009.

[2] Фисун А.Я., Кучмин А.Н., Акимкин В.Г. и др. Свиной грипп: эпидемиология, диагностика, лечение и профилактика./ Военно - медицинский журнал/том CCCXXX/07.2009.С.46 - 54.

[3] Чучалин А.Г. Тяжёлые формы гриппа: диагностические и лечебные алгоритмы / Пульмонология №5, 2009.С. 5-7.

[4] Чучалин А.Г., Черняев А.Л., Зайратьянц О.В. и др. Патологическая анатомия лёгких при гриппе А(H1N1), по данным аутопсий./ Пульмонология №1; 2010. С.5-10.

[5] Dawood F.S., Jains S., Finelli L. et al. Emergence of a novel swine-origen influenza a (h1n1) virus in humans. N. Engl. J. Med. 2009; 360: 2605-2615.

[6] Dominuez-Cherit G., Lapinsky S.E, Macias A.E. et al. Criticalli 111 patients with 2009 influenza A (H1N1) in Mexico. J.A.M.A. 2009; 302 (17): 1880-1887.

[7] Mauad T., Hajjar L.A., Callegari G. de S. et al. Lung pathology in phatal novel human influenza a (h1n1) infection. ARJCCM Articles in Press. Published on October 29, 2009 as doi:10.1164/rccm.200909-1420OC.

RIGHTS & PERMISSIONS

Abrosimov V.N., Almazova E.V., Abrosimov V.N., Almazova E.V.