Analysis of Prevalence of Lower Extremity Varicose Vein Disease of in One of Major Regions of Central Federal District of Russian Federation Using Multi-Variant Approach

Abstract

INTRODUCTION: The majority of epidemiological studies on lower extremity varicose veins (LEVV) published to date have cross-sectional character, therefore, understanding the relationships between the disease and other epidemiological variables in them is mainly based on data analysis in a short period of time and does not take into account the influence on the main parameters of functioning national health systems. It is relevant to analyze the epidemiological parameters of LEVV in the long term, taking into account the influence of the state health system in a large region of the Russian Federation.

AIM: To identify changes in the distribution of LEVV in different territories of the Yaroslavl region (YaR) over 10 years (2011–2021).

MATERIALS AND METHODS: A retrospective study of statistical parameters of the work of medical organizations of the YaR in 2011–2021 was conducted, namely, of the total number of attached adult population, the dynamics of the number of attached population, the total number and dynamics of the number of patients with the established diagnosis of LEVV. The weighted average value for continuous variables with a 95% confidence interval (CI) was evaluated. Heterogeneity was evaluated based on the I² value.

RESULTS: The static weighted average value of the prevalence of LEVV in Yaroslavl at the end of the year in 2011–2021 was 1.040% (95% CI: 1.031–1.049). When analyzing the data for 2011–2021, the trend for a decline in the recorded prevalence of LEVV was determined. At the end of 2021, the prevalence of LEVV in Yaroslavl declined by 0.715%, in Pereslavl district — by 0.466%, in Tutaev district — by 0.4%, in Rostov district — by 0.392%, in Rybinsk — by 0.192% with high heterogeneity of data depending on the territory and period (I² > 99). Besides, during the analyzed 10 years, there occurred significant changes in approaches to surgical treatment of LEVV, such as appearance of hospital-substituting technologies that have become widely used in the territory of the YaR by non-governmental medical organizations in the vast majority of cases.

CONCLUSIONS: According to official data, the decline in the morbidity with LEVV in the studied territories of the YaR over 10 years (2011–2021) contradicts the published results of epidemiological studies. The information obtained, together with the high heterogeneity of statistical data for individual territories and periods, may indirectly indicate the low efficiency of the existing system of providing medical care to the population with LEVV.

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