Advances in surgical thresholds for ascending aortic aneurysms: an expert perspective

Jinlin Wu

Vessel Plus ›› 2025, Vol. 9 ›› Issue (1) : 31

PDF
Vessel Plus ›› 2025, Vol. 9 ›› Issue (1) :31 DOI: 10.20517/2574-1209.2025.61
Perspective

Advances in surgical thresholds for ascending aortic aneurysms: an expert perspective

Author information +
History +
PDF

Abstract

The ascending aortic aneurysm represents a critical clinical concern due to its potential for catastrophic complications. With global demographic shifts toward aging populations, the incidence of ascending aortic aneurysms is projected to rise significantly. This brief perspective examines the evolution of our understanding regarding the natural history of ascending aortic aneurysms and the refinement of surgical intervention criteria over time. We discuss the transition from simplistic diameter-based metrics to multidimensional assessment approaches that consider patient-specific factors, including anatomical variations, biomechanical properties, and genetic predispositions. Recent paradigm shifts, such as the recalibration of diameter thresholds from 5.5 cm to 5.0 cm and the integration of volumetric analysis, highlight the field's progression toward more precise risk stratification. This paper aims to provide clinicians with a contemporary framework for surgical decision-making while identifying promising avenues for further refinement of intervention strategies.

Keywords

Aortic aneurysm / surgical indicator / natural history

Cite this article

Download citation ▾
Jinlin Wu. Advances in surgical thresholds for ascending aortic aneurysms: an expert perspective. Vessel Plus, 2025, 9(1): 31 DOI:10.20517/2574-1209.2025.61

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Peterss S,Zafar MA.Elective surgery for ascending aortic aneurysm in the elderly: should there be an age cut-off?.Eur J Cardiothorac Surg2017;51:965-70

[2]

Joyce JW,Kincaid OW.Aneurysms of the Thoracic Aorta: a clinical study with special reference to prognosis.Circulation1964;29:176-81

[3]

Coady MA,Hammond GL.What is the appropriate size criterion for resection of thoracic aortic aneurysms?.J Thorac Cardiovasc Surg1997;113:476-91; discussion 489

[4]

Zafar MA,Rizzo JA.Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm.J Thorac Cardiovasc Surg2018;155:1938-50

[5]

Czerny M,Berger T.EACTS/STS guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ.Ann Thorac Surg2024;118:5-115

[6]

Isselbacher EM,Hamilton Black J 3rd.2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on clinical practice guidelines.Circulation2022;146:e334-482

[7]

Krüger T,Veseli K.Ascending aortic elongation and the risk of dissection.Eur J Cardiothorac Surg2016;50:241-7

[8]

Wu J,Li Y.Ascending aortic length and risk of aortic adverse events: the neglected dimension.J Am Coll Cardiol2019;74:1883-94

[9]

Pape LA,Isselbacher EM.Aortic diameter ≥5.5 cm is not a good predictor of type A aortic dissection: observations from the International Registry of Acute Aortic Dissection (IRAD).Circulation2007;116:1120-7

[10]

Wu J,Liu Y.Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University.Eur Heart J2023;44:4579-88

[11]

Zafar MA,Wu J.Natural history of descending thoracic and thoracoabdominal aortic aneurysms.J Thorac Cardiovasc Surg2021;161:498-511.e1

[12]

Xiao M,Chen D.Ascending aortic volume: a feasible indicator for ascending aortic aneurysm elective surgery?.Acta Biomater2023;167:100-8

[13]

Milewicz DM,Hostetler E,Pinard AC.Update on the genetic risk for thoracic aortic aneurysms and acute aortic dissections: implications for clinical care.J Cardiovasc Surg2021;62:203-10

[14]

Ostberg NP,Ziganshin BA.The genetics of thoracic aortic aneurysms and dissection: a clinical perspective.Biomolecules2020;10:182 PMCID:PMC7072177

[15]

Zafar MA,Vinholo TF.Bicuspid aortopathy does not require earlier surgical intervention.J Thorac Cardiovasc Surg2024;168:760-9.e4

[16]

Wu J,Li X.Aortic size distribution among normal, hypertension, bicuspid, and Marfan populations.Eur Heart J2023;1:qyad19 PMCID:PMC11195692

[17]

Hirad A,Raterman B.Feasibility of measuring magnetic resonance elastography-derived stiffness in human thoracic aorta and aortic dissection phantoms.J Vasc Surg Cases Innov Tech2025;11:101697

[18]

Singh P,Salata B.Role of molecular imaging with positron emission tomography in aortic aneurysms.J Thorac Dis2017;9:S333-42 PMCID:PMC5422660

[19]

Golledge J,Dalman RL.Circulating markers of abdominal aortic aneurysm presence and progression.Circulation2008;118:2382-92 PMCID:PMC2752737

[20]

Molacek J,Treska V,Baxa J.Proteomic analysis of the abdominal aortic aneurysm wall.Surg Today2014;44:142-51

[21]

Svensson LG.Aortic cross-sectional area/height ratio timing of aortic surgery in asymptomatic patients with Marfan syndrome.J Thorac Cardiovasc Surg2002;123:360-1

PDF

48

Accesses

0

Citation

Detail

Sections
Recommended

/