PDF
Abstract
Choice of conduit remains the Achilles heel of coronary artery bypass grafting. Conduit choice is crucial as it is deemed to influence the long-term outcomes. While the important survival advantage of a left internal mammary artery graft over vein grafts is universally accepted, controversy reigns supreme regarding the next best conduit. There is plenty of evidence to suggest that arterial grafts are not only superior in terms of patency and survival, but they also protect the native coronary arteries against further progression of atherosclerotic disease. Total arterial coronary grafting, utilizing various configurations of bilateral internal mammary arteries, radial artery and occasionally right gastroepiploic artery is a safe and reproducible strategy. However, concerns about additional operative time, enhanced technical complexity, graft spasm with hypoperfusion, competitive flow, increased risk of bleeding, deep sternal wound infection, and most importantly lack of randomized trial data have prevented the universal adoption of total arterial coronary grafting. This review evaluates the currents outcomes of total arterial coronary grafting and summarizes the concerns and controversies associated with this strategy.
Keywords
Coronary artery bypass grafting
/
bilateral internal mammary artery grafting
/
multiple arterial grafting
/
total arterial grafting
/
total arterial revascularization
Cite this article
Download citation ▾
Shahzad G. Raja.
Total arterial coronary grafting: outcomes, concerns and controversies.
Vessel Plus, 2019, 3(1): 23 DOI:10.20517/2574-1209.2019.05
| [1] |
Schwann TA.The surgical treatment of coronary artery occlusive disease: modern treatment strategies for an age old problem..Surg Clin North Am2017;97:835-65
|
| [2] |
Raja SG.Endoscopic vein harvesting: technique, outcomes, concerns & controversies..J Thorac Dis.2013;5 Suppl 6:S630-7 PMCID:PMC3831843
|
| [3] |
Motwani JG.Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and prevention..Circulation1998;97:916-31
|
| [4] |
Loop FD,Cosgrove DM,Goormastic M.Inference of the internal mammary artery graft on 10 year survival and other cardiac events..N Engl J Med1986;314:1-6
|
| [5] |
Lytle BW,Loop FD,Arnold JH.Two internal thoracic artery grafts are better than one..J Thorac Cardiovasc Surg1999;117:855-72
|
| [6] |
Pick AW,Anderson BJ.Single versus bilateral internal mammary artery grafts: 10-year outcome analysis..Ann Thorac Surg1997;64:599-605
|
| [7] |
Buxton BF,Fuller JA.Bilateral internal thoracic artery grafting may improve outcome of coronary artery surgery. Risk-adjusted survival..Circulation1998;98:II1-6
|
| [8] |
Dimitrova KR,Geller CN,Ko W.Arterial grafts protect the native coronary vessels from atherosclerotic disease progression..Ann Thorac Surg2012;94:475-81
|
| [9] |
Royse AG,Shah P,Kaushik S.Radial artery harvest technique, use and functional outcome..Eur J Cardiothorac Surg1999;15:186-93
|
| [10] |
Falk V.Coronary bypass grafting with bilateral internal thoracic arteries..Heart2013;99:821
|
| [11] |
Mohr FW,Kappetein AP,Ståhle E.Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial..Lancet2013;381:629-38
|
| [12] |
Taggart DP.How I deploy arterial grafts..Ann Cardiothorac Surg2018;7:690-7 PMCID:PMC6219946
|
| [13] |
Raja SG.Surgical strategies for bilateral internal mammary artery grafting..Int J Surg2015;16:140-5
|
| [14] |
Lev-Ran O,Matsa M,Kramer A.Arterial myocardial revascularization with in situ crossover right internal thoracic artery to left anterior descending artery..Ann Thorac Surg2001;72:798-803
|
| [15] |
Puig LB,Rati M,da Luz PL.A technique of anastomosis of the right internal mammary artery to the circumflex artery and its branches..Ann Thorac Surg1984;38:533-4
|
| [16] |
Paterson HS,Byth K,Denniss AR.Full myocardial revascularization with bilateral internal mammary artery Y grafts..Ann Cardiothorac Surg2013;2:444-52 PMCID:PMC3741876
|
| [17] |
Yoshizumi T,Maekawa A,Wakai K.Is the mid-term outcome of free right internal thoracic artery with a proximal anastomosis modification inferior to in situ right internal thoracic artery?.Gen Thorac Cardiovasc Surg2012;60:480-8
|
| [18] |
Damgaard S,Lilleør NB,Sander K.Comparable three months’ outcome of total arterial revascularization versus conventional coronary surgery: copenhagen arterial revascularization randomized patency and outcome trial..J Thorac Cardiovasc Surg2008;135:1069-75
|
| [19] |
Tatoulis J,Fuller JA.Total arterial coronary revascularization: techniques and results in 3,220 patients..Ann Thorac Surg1999;68:2093-9
|
| [20] |
Formica F,Greco P,Gastaldi D.Long-term follow-up of total arterial myocardial revascularization using exclusively pedicle bilateral internal thoracic artery and right gastroepiploic artery..Eur J Cardiothorac Surg2004;26:1141-8
|
| [21] |
Muneretto C,Manfredi J,Rodella G.Safety and usefulness of composite grafts for total arterial myocardial revascularization: a prospective randomized evaluation..J Thorac Cardiovasc Surg2003;125:826-35
|
| [22] |
Zhao DF,Seco M,Wilson MK.Coronary artery bypass grafting with and without manipulation of the ascending aorta: a network meta-analysis..J Am Coll Cardiol2017;69:924-36
|
| [23] |
Muneretto C,Bisleri G,Terrini A.Is total arterial myocardial revascularization with composite grafts a safe and useful procedure in the elderly?.Eur J Cardiothorac Surg2003;23:657-64
|
| [24] |
Muneretto C,Negri A,Metra M.Total arterial myocardial revascularization with composite grafts improves results of coronary surgery in elderly: a prospective randomized comparison with conventional coronary artery bypass surgery..Circulation.2003;108 Suppl 1:II29-33
|
| [25] |
Muneretto C,Negri A,Carone E.Left internal thoracic artery-radial artery composite grafts as the technique of choice for myocardial revascularization in elderly patients: a prospective randomized evaluation..J Thorac Cardiovasc Surg2004;127:179-84
|
| [26] |
Tavilla G,Putter H.Twenty-year outcomes of coronary artery bypass grafting utilizing 3 in situ arterial grafts..J Thorac Cardiovasc Surg2018;
|
| [27] |
Tatoulis J,Skillington PD.Total arterial revascularization: achievable and prognostically effective-a multicentre analysis..Ann Thorac Surg2015;100:1268-75
|
| [28] |
Yanagawa B,Mazine A,Jüni P.Impact of total arterial revascularization on long term survival: A systematic review and meta-analysis of 130,305 patients..Int J Cardiol2017;233:29-36
|
| [29] |
Royse AG,Groves KL,Yu G.Blood flow in composite arterial grafts and effect of native coronary flow..Ann Thorac Surg1999;68:1619-22
|
| [30] |
Sakaguchi G,Ohnaka M,Nishimura K.Composite arterial Y graft has less coronary flow reserve than independent grafts..Ann Thorac Surg2002;74:493-6
|
| [31] |
Affleck DG,Bailey MS,Maniar H.Flow dynamics of the internal thoracic and radial artery T-graft..Ann Thorac Surg2004;78:1290-4
|
| [32] |
Wendler O,Markwirth T,Tscholl D.T grafts with the right internal thoracic artery to left internal thoracic artery versus the left internal thoracic artery and radial artery: flow dynamics in the internal thoracic artery main stem..J Thorac Cardiovasc Surg1999;118:841-8
|
| [33] |
Raja SG.Composite arterial grafting..Expert Rev Cardiovasc Ther2006;4:523-33
|
| [34] |
Orlov B,Kogan A,Zlotnick AY.Multiple arterial revascularization using the tangential K-graft technique..Ann Thorac Surg2005;80:1948-50
|
| [35] |
Nakajima H,Tagusari O,Niwaya K.Competitive flow in arterial composite grafts and effect of graft arrangement in off-pump coronary revascularization..Ann Thorac Surg2004;78:481-6
|
| [36] |
Pagni S,Ballen J,Chiang BY.ITA versus SVG: a comparison of instantaneous pressure and flow dynamics during competitive flow..Eur J Cardiothorac Surg1997;11:1086-92
|
| [37] |
Taggart DP,Gray AM,Nugara F.Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularisation Trial (ART)..Eur Heart J2010;31:2470-81
|
| [38] |
De Paulis R,Scaffa R,Zeitani J.The effect of bilateral internal thoracic artery harvesting on superficial and deep sternal infection: The role of skeletonization..J Thorac Cardiovasc Surg2005;129:536-43
|
| [39] |
Kamiya H,Martens A,Haverich A.Sternal microcirculation after skeletonized versus pedicled harvesting of the internal thoracic artery: a randomized study..J Thorac Cardiovasc Surg2008;135:32-7
|
| [40] |
Benedetto U,Gerry S,Lees B.Pedicled and skeletonized single and bilateral internal thoracic artery grafts and the incidence of sternal wound complications: Insights from the Arterial Revascularization Trial..J Thorac Cardiovasc Surg2016;152:270-6
|
| [41] |
Benedetto U,Zakkar M,Angelini GD.Are three arteries better than two? Impact of using the radial artery in addition to bilateral internal thoracic artery grafting on long-term survival..J Thorac Cardiovasc Surg2016;152:862-9.e2
|
| [42] |
Rosengart TK.Total arterial revascularization: when will its time come?.J Thorac Cardiovasc Surg2014;148:1244-5
|
| [43] |
Di Mauro M,Iacò AL,Gagliardi M.Bilateral internal thoracic artery on the left side: a propensity score-matched study of impact of the third conduit on the right side..J Thorac Cardiovasc Surg2009;137:869-74
|
| [44] |
Glineur D.Importance of the third arterial graft in multiple arterial grafting strategies..Ann Cardiothorac Surg2013;2:475-80 PMCID:PMC3741880
|
| [45] |
Grau JB,Johnson CK,Zapolanski A.The effects of using a radial artery in patients already receiving bilateral internal mammary arteries during coronary bypass grafting: 30-day outcomes and 14-year survival in a propensity-matched cohort..Eur J Cardiothorac Surg2016;49:203-10
|
| [46] |
Locker C,Dearani JA,Park SJ.Multiple arterial grafts improve late survival of patients undergoing coronary artery bypass graft surgery: analysis of 8622 patients with multivessel disease..Circulation2012;126:1023-30
|
| [47] |
Mohammadi S,Voisine P,Charbonneau E.Impact of the radial artery as an additional arterial conduit during in-Ssitu bilateral internal mammary artery grafting: a propensity score-matched study..Ann Thorac Surg2016;101:913-8
|
| [48] |
Nasso G,Lamarra M,Coppola R.Impact of arterial revascularization in patients undergoing coronary bypass..J Card Surg2012;27:427-33
|
| [49] |
Shi WY,Newcomb AE,Fuller JA.Is a third arterial conduit necessary? Comparison of the radial artery and saphenous vein in patients receiving bilateral internal thoracic arteries for triple vessel coronary disease..Eur J Cardiothorac Surg2016;50:53-60
|
| [50] |
Luthra S,Matuszewski M,Billing JS.Does a third arterial conduit to the right coronary circulation improve survival?.J Thorac Cardiovasc Surg2018;155:855-60.e2
|
| [51] |
Formica F,Singh G,Messina LA.The impact of the radial artery or the saphenous vein in addition to the bilateral internal mammary arteries on late survival: A propensity score analysis..J Thorac Cardiovasc Surg2019;S0022-5223(19)30005-4
|
| [52] |
Gaudino M,Di Franco A,Iannaccone M.Three arterial grafts improve late survival: a meta-analysis of propensity-matched studies..Circulation2017;135:1036-44
|
| [53] |
Shi WY,Tatoulis J,Newcomb AE.Are all forms of total arterial revascularization equal? A comparison of single versus bilateral internal thoracic artery grafting strategies..J Thorac Cardiovasc Surg2015;150:1526-331534.e1-3
|
| [54] |
Navia D,Piccinini F,Thierer J.Is the second internal thoracic artery better than the radial artery in total arterial off-pump coronary artery bypass grafting? A propensity score-matched follow-up study..J Thorac Cardiovasc Surg2014;147:632-8
|
| [55] |
Taggart DP,Gerry S,Gray AM.Bilateral versus single internal-thoracic-artery grafts at 10 years..N Engl J Med2019;380:437-46
|
| [56] |
Gaudino M,Bakaeen FG,Barili F.Randomized comparison of the clinical outcome of single versus multiple arterial grafts: the ROMA trial-rationale and study protocol..Eur J Cardiothorac Surg2017;52:1031-40
|