Prostate biopsy is the gold standard for diagnosing prostate cancer (PCa). Prostate targeted biopsy (TB) having a higher rate of detecting clinically significant PCa (csPCa) than traditional systematic biopsy (SB) is supported by high‐quality evidence. However, the TB indications and strategies are controversial. The National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences, invited a panel of recognized urology experts in PCa to address these topics at the Panjiayuan Consensus Conference 2022. The conference results on prostate TB are presented herein. The National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences identified 10 key areas of prostate biopsy: (1) selection of imaging examination; (2) indications of TB; (3) transperineal and transrectal prostate biopsy; (4) TB pathways; (5) TB and SB; (6) three techniques of TB; (7) the number of TB cores needed for one lesion; (8) core number for SB; (9) free‐hand TB; (10) future development of TB/prostate diagnosis. Thus, a panel of 25 recognized urologists and 2 radiologists from China were invited to attend this conference. The panel voted anonymously on 14 predetermined questions. Voting was based on the panelists' clinical practice and opinion, rather than high‐level evidence. The voting outcomes were supported by the panel unequally, and details of the voting results were reported. The voting results can help clinicians to decide on biopsy timing and proper strategies, for which guidelines are sparse. We also focused on the future development of TB and SB, such as the combined pathway of TB and SB, techniques of TB, biopsy cores, free‐hand TB, and prostate‐specific membrane antigen positron emission tomography/ computed tomography.
Bladder cancer represents one of the most prevalent malignant tumors affecting the urinary system. As per data disclosed by the National Cancer Registration Center of China in 2019, the incidence of bladder cancer was 5.80 per 100,000 in 2015, placing it as the thirteenth most common systemic malignancy. Bladder cancer poses a substantial threat to public health in China, underlining the critical importance of standardizing diagnosis and treatment to enhance clinical outcomes. This clinical practice guideline for bladder cancer centers on the etiologies, clinical presentations, and diagnostic procedures for suspected bladder cancer, in addition to the histopathology and staging of urothelial bladder cancer.
The fifth generation of mobile communication technology (5G technology) features large system capacity, fast data transmission rate, support for large‐scale device connection, low latency, and high reliability. With the development and popularization of 5G technology, it is also widely used in medicine. In recent years, 5G telesurgery has been paid attention to and made continuous progress, and the research related to its combination with urology has also made significant achievements. We collect the combination of 5G technology and urology improves the uneven distribution of medical resources, provides timely, high‐quality remote surgical interventions for urology patients, reduces the financial burden on patients, surgical complications, and the difficulty of accessing medical care from a distance, and brings new opportunities for medical development.
Given that urine‐derived stem cells (USCs) originate from the urinary tract system, they hold great potential for treating urological disorders. USCs have several advantages over other types of stem cells, such as easy and noninvasive collection, and abundant supply. USCs can differentiate into different types of cells. This makes them a potential source of cells for tissue engineering and regenerative medicine in the field of urology. In animal models, USCs or USC‐derived exosomes regenerate damaged tissues in the treatment of various urological disorders such as urinary incontinence, bladder dysfunction, interstitial cystitis, urethra injury erectile dysfunction, and kidney injury via multiple differentiation potential, angiogenesis, anti‐inflammatory, paracrine effects, and immune modulation capability. Overall, the use of USCs in urological disorders is a rapidly developing field, and ongoing research is needed to fully understand their potential applications. However, the early results are promising and suggest that USCs could become a valuable cell source for the treatment of various urological disorders in the future.
Background: Penile fracture is defined as the rupture of the tunica albuginea of the corpora cavernosa while in an erect state, during mostly intercourse or masturbation. Diagnosis of such condition is mainly clinical, while on the other hand, seeking medical attention is often delayed, and treatment options depend upon the time of presentation.
Methods: This case report details a patient who developed a penile cystic fibro‐hematoma lesion, 2 months after a neglected penile fracture. After proper assessment including detailed history, physical exam and a penile doppler ultrasound, patient was elected for surgery.
Results: The patient underwent surgical removal of the mass, correction of the curvature, and reinforcement of the weakened tunica albuginea with a pericardium graft. Postoperative course was uneventful. At follow‐up, he reported normal erectile function with resolved penile curvature.
Conclusion: This highlights the importance of seeking prompt medical attention for suspected penile fractures to avoid potential long‐term complications.