Aims:
Thrombosis and Circulation Research is an international, peer-reviewed journal dedicated to publishing high-quality research and reviews in the field of thrombosis, vascular biology, and circulatory disorders. The journal aims to bridge the gap between basic science and clinical applications, fostering the translation of laboratory discoveries into innovative therapeutic strategies for cardiovascular diseases, thrombosis, and related disorders.
Scope:
Thrombosis and Circulation Research covers a wide array of topics related to thrombosis, vascular biology, and circulation research, with a particular emphasis on translational and interdisciplinary research. It seeks to publish cutting-edge studies on the molecular, cellular, and systemic mechanisms underlying thrombotic and vascular diseases, as well as advances in diagnostic and therapeutic approaches. The scope includes, but is not limited to, the following areas:
● Thrombosis and Hemostasis:
○ Pathophysiology of thrombosis (venous and arterial)
○ Platelet function and aggregation
○ Coagulation and fibrinolysis mechanisms
○ Anticoagulant therapies and resistance
○ Genetic and acquired thrombotic disorders
● Vascular Biology:
○ Endothelial cell function and dysfunction
○ Vascular smooth muscle cell biology
○ Angiogenesis, vascular remodeling, and regeneration
○ Vascular inflammation and immune responses
○ Vascular biomarkers and their diagnostic potential
● Cardiovascular and Pulmonary Diseases:
○ Stroke, myocardial infarction, and other thromboembolic events
○ Atherosclerosis and arterial diseases
○ Hypertension and its vascular effects
○ Pulmonary embolism and deep vein thrombosis
○ Pulmonary hypertension and other pulmonary circulation disorders
○ Post-thrombotic syndrome and vascular complications in chronic disease
● Innovative Therapies and Drug Development:
○ Targeted therapies in thrombosis and vascular diseases
○ Advances in antithrombotic drugs and drug delivery systems
○ Gene therapy and RNA-based therapeutics for thrombotic and vascular diseases
○ Nanomedicine and drug delivery for cardiovascular and thrombotic conditions
● Emerging Technologies in Vascular and Thrombosis Research:
○ Omics in thrombosis and vascular diseases
○ Artificial intelligence and machine learning in vascular research
○ High-throughput screening and precision medicine approaches
○ 3D cell culture models and organ-on-a-chip technologies for vascular studies
● Clinical Research and Translational Studies:
○ Clinical trials in thrombosis prevention, diagnosis, and treatment
○ Risk factors, epidemiology, and prevention strategies for thrombotic disorders
○ Advances in diagnostic imaging and molecular diagnostics for vascular diseases
○ Personalized medicine approaches in thrombosis and circulation management
● Interdisciplinary Research:
○ The intersection of vascular diseases with metabolic diseases (e.g., diabetes, obesity)
○ The role of inflammation, immune system, and microbiota in thrombosis and vascular diseases
○ Interaction between thrombosis and cancer (e.g., cancer-associated thrombosis)
○ Vascular complications in aging and neurodegenerative diseases