The impact of physical activity intensity and sleep duration on cognitive function: The mediating and moderating roles of sleep duration

Yanfei Zhang , Bo Wang , Nan Jin , Yihao Wang , Guorui Liu

Sleep Research ›› 2025, Vol. 2 ›› Issue (4) : 240 -248.

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Sleep Research ›› 2025, Vol. 2 ›› Issue (4) :240 -248. DOI: 10.1002/slp2.70018
RESEARCH ARTICLE
The impact of physical activity intensity and sleep duration on cognitive function: The mediating and moderating roles of sleep duration
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Abstract

Objective: To examine the associations between physical activity (PA), sleep duration, and cognitive function among middle-aged and older adults, focusing on the mediating and moderating roles of sleep duration.

Methods: Data were derived from the 2020 wave of the China Health and Retirement Longitudinal Study. A cross-sectional design was employed. Multiple linear regression and PROCESS Models 1 and 4 were used to analyze the effects of PA intensity and sleep duration on cognitive function, as well as their interactive relationships.

Results: Sleep duration was a significant positive predictor of cognitive function (B = 0.214, p < 0.001). Moderate- and light-intensity PA were negatively associated with cognitive performance (B = −1.068 and B = −1.401, p < 0.001), whereas vigorous-intensity PA was positively associated (B = 0.546, p < 0.001). Sleep duration buffered the negative effect of moderate-intensity PA on cognition but amplified the detrimental effect of light-intensity activity. Moreover, sleep duration suppressed the positive association between vigorous PA and cognitive function.

Conclusion: PA and sleep duration appear to be associated with cognitive function through interaction and mediation pathways. Optimizing both PA and sleep behaviors may contribute to the preservation of cognitive function.

Keywords

cognitive function / mediation / moderation / older adults in China / physical activity / sleep duration

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Yanfei Zhang, Bo Wang, Nan Jin, Yihao Wang, Guorui Liu. The impact of physical activity intensity and sleep duration on cognitive function: The mediating and moderating roles of sleep duration. Sleep Research, 2025, 2(4): 240-248 DOI:10.1002/slp2.70018

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References

[1]

Wang Q, Zhu H, Dai R, Zhang T. Associations between total sleep duration and cognitive function among middle-aged and older Chinese adults: does midday napping have an effect on it? Int J Gen Med. 2022; 15: 1381-1391. https://doi.org/10.2147/IJGM.S343286

[2]

Hu Y, Xia X, Li H, et al. The association between sleep quality and cognitive impairment among a multi-ethnic population of middle-aged and older adults in Western China: a multi-center cross-sectional study. Front Public Health. 2025; 13:1500027. https://doi.org/10.3389/fpubh.2025.1500027

[3]

Jedrziewski MK, Lee VM, Trojanowski JQ. Physical activity and cognitive health. Alzheimer's Dement. 2007; 3(2): 98-108. https://doi.org/10.1016/j.jalz.2007.01.009

[4]

Zhu X, Yin S, Lang M, He R, Li J. The more the better? A meta-analysis on effects of combined cognitive and physical intervention on cognition in healthy older adults. Ageing Res Rev. 2016; 31: 67-79. https://doi.org/10.1016/j.arr.2016.07.003

[5]

López-Ortiz S, Lista S, Valenzuela PL, et al. Effects of physical activity and exercise interventions on alzheimer’s disease: an umbrella review of existing meta-analyses. J Neurol. 2023; 270(2): 711-725. https://doi.org/10.1007/s00415-022-11454-8

[6]

Kraft E. Cognitive function, physical activity, and aging: possible biological links and implications for multimodal interventions. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2012; 19(1-2): 248-263. https://doi.org/10.1080/13825585.2011.645010

[7]

Erickson KI, Donofry SD, Sewell KR, Brown BM, Stillman CM. Cognitive aging and the promise of physical activity. Annu Rev Clin Psychol. 2022; 18(1): 417-442. https://doi.org/10.1146/annurev-clinpsy-072720-014213

[8]

Deng Q, Zhou J. The mediating effect of sleep duration and sleep quality on physical ac-tivity and cognitive function of rural. Mod Prev Med. 2024; 51: 1244-1248. https://doi.org/10.20043/j.cnki.MPM.202401129

[9]

Najar J, östling S, Gudmundsson P, et al. Cognitive and physical activity and dementia. Neurology. 2019; 92(12): 92. https://doi.org/10.1212/WNL.0000000000007021

[10]

Ma X, Li S, Jia S, Liu C, Zhang Z, Han D. Relationship of physical activity and cognitive function to sleep quality in older adults with cognitive impairment: a mediating effect of resting eeg. Chin J Rehabil Theory Pract. 2024; 30: 1442-1451.

[11]

Kim K, Hwang G, Cho YH, et al. Relationships of physical activity, depression, and sleep with cognitive function in community-dwelling older adults. Int J Environ Res Publ Health. 2022; 19(23):15655. https://doi.org/10.3390/ijerph192315655

[12]

Devore EE, Grodstein F, Schernhammer ES. Sleep duration in relation to cognitive function among older adults: a systematic review of observational studies. Neuroepidemiology. 2016; 46(1): 57-78. https://doi.org/10.1159/000442418

[13]

Chen L, Li D, Tang K, Li Z, Xiaoyun H. Sleep duration and leisure activities are involved in regulating the association of depressive symptoms, muscle strength, physical function and mild cognitive impairment. Heliyon. 2024; 10(13):e33832. https://doi.org/10.1016/j.heliyon.2024.e33832

[14]

Tao H, Wang T, Jia Y. Joint association of sleep duration and physical activity with cognitive performance among Chinese adults: an analysis of nationally representative survey data. Front Public Health. 2023; 11:1244407. https://doi.org/10.3389/fpubh.2023.1244407

[15]

Zhao Y, Hu Y, Smith JP, Strauss J, Yang G. Cohort profile: the China health and retirement longitudinal study (charls). Int J Epidemiol. 2014; 43(1): 61-68. https://doi.org/10.1093/ije/dys203

[16]

Tao H, Wang T, Jia YQ. Joint association of sleep duration and physical activity with cognitive performance among Chinese adults: an analysis of nationally representative survey data. Front Public Health. 2023; 11:1244407. https://doi.org/10.3389/fpubh.2023.1244407

[17]

Zhou S, Chen S, Liu X, Zhang Y, Zhao M, Li W. Physical activity improves cognition and activities of daily living in adults with alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials. Int J Environ Res Publ Health. 2022; 19(3):1216. https://doi.org/10.3390/ijerph19031216

[18]

Peng Y, Zhang G, Pang H. Impact of short-duration aerobic exercise intensity on executive function and sleep. 2025. https://doi.org/10.48550/arxiv.2503.09077

[19]

Latino F, Tafuri F. Physical activity and cognitive functioning. Medicina. 2024; 60(2):216. https://doi.org/10.3390/medicina60020216

[20]

Hsiao C, Wen CJ, Yen HY, Hsueh M, Liao Y. Association between accelerometer-measured light-intensity physical activity and cognitive function in older adults. J Nutr health aging. 2022; 26(3): 230-235. https://doi.org/10.1007/s12603-022-1749-0

[21]

Geng Q, Sun L, Zhang Y, zheng G. Mediating effect of sleep quality and cognitive reserve on depressive symptoms and cognitive function in community-dwelling elderly people. Mod Prev Med. 2024; 51: 2609-2614. https://doi.org/10.20043/j.cnki.MPM.202403144

[22]

Lo JC, Groeger JA, Cheng GH, Dijk DJ, Chee MW. Self-reported sleep duration and cognitive performance in older adults: a systematic review and meta-analysis. Sleep Med. 2016; 17: 87-98. https://doi.org/10.1016/j.sleep.2015.08.021

[23]

Ma Y, Liang L, Zheng F, Shi L, Zhong B, Xie W. Association between sleep duration and cognitive decline. JAMA Netw Open. 2020; 3(9):e2013573. https://doi.org/10.1001/jamanetworkopen.2020.13573

[24]

Chen W, Wang X. Longitudinal associations between sleep duration and cognitive impairment in Chinese elderly. Front Aging Neurosci. 2022; 14:1037650. https://doi.org/10.3389/fnagi.2022.1037650

[25]

Mellow ML, Crozier AJ, Dumuid D, et al. How are combinations of physical activity, sedentary behaviour and sleep related to cognitive function in older adults? A systematic review. Exp Gerontol. 2022; 159:111698. https://doi.org/10.1016/j.exger.2022.111698

[26]

Huang SY, Li YZ, Zhang YR, et al. Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK biobank participants. Mol Psychiatry. 2022; 27(10): 4343-4354. https://doi.org/10.1038/s41380-022-01655-y

[27]

Bidzan-Bluma I, Lipowska M. Physical activity and cognitive functioning of children: a systematic review. Int J Environ Res Publ Health. 2018; 15(4):800. https://doi.org/10.3390/ijerph15040800

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2025 The Author(s). Sleep Research published by John Wiley & Sons Australia, Ltd on behalf of Chinese Sleep Research Society.

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