Comments on “On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy”

Zhaoning Wang; Linlin Wang

doi:10.1002/pro6.70026

Precision Radiation Oncology ›› 2025, Vol. 9 ›› Issue (3) : 221 -222. DOI: 10.1002/pro6.70026

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Comments on “On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy”

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Zhaoning Wang, Linlin Wang. Comments on “On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy”. Precision Radiation Oncology, 2025, 9(3): 221-222 DOI:10.1002/pro6.70026

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References

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[3]	Li H, Mayr NA, Griffin RJ, et al. Overview and Recommendations for Prospective Multi-institutional Spatially Fractionated Radiation Therapy Clinical Trials. Int J Radiat Oncol Biol Phys. 2024; 119(3): 737-749.

[4]	Sammer M, Dombrowsky AC, Schauer J, et al. Normal Tissue Response of Combined Temporal and Spatial Fractionation in Proton Minibeam Radiation Therapy. Int J Radiat Oncol Biol Phys. 2021; 109(1): 76-83.

[5]	Acuña MI, Lamirault C, Larcher T, et al. Mini-GRID therapy delivers optimised spatially fractionated radiation therapy using a flattening free filter accelerator. Commun Med (Lond). 2025; 5(1): 101.

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