Pathology serves as the bridge between basic medical sciences and clinical practice, investigating disease etiology, pathogenesis, morphological alterations, and functional disturbance[
1]. Its fundamental mission — to accurately diagnose diseases — remains particularly vital in managing complex conditions such as oncology, cardiovascular and respiratory diseases, neurological disorders and metabolic diseases[
2]. Of these, cancer represents a profound global challenge. Current epidemiological data indicate that in 2020, approximately 19.3 million new cancer cases and 10.0 million cancer-related deaths occurred worldwide[
3]. In China alone, approximately 4.82 million new cancer cases and 2.57 million cancer-related deaths were reported in 2022[
4]. A deep understanding of cancer pathology is essential for effective diagnosis, treatment, and prevention of this disease. As a specialized branch of medicine, pathology enables precise identification of cancer types, determination of disease extent, prediction of patient outcomes, and guidance of therapeutic strategy. The integrated application of histopathology, cytopathology, molecular pathology, and laboratory medicine supports comprehensive cancer care and facilitates truly personalized treatment approaches.
Despite the existence of several pathology-focused journals, the rapid advancement of life science technologies and deepening interdisciplinary integration are driving an unprecedented transformation of clinical pathology and research. The integration of cutting-edge techniques, including multimodal fusion model, spatial multiomics profiling, single-cell sequencing, and artificial intelligence, has profoundly shifted pathological research from traditional morphological observation towards multi-dimensional, high-throughput integrative analysis[
5]. Furthermore, the emerging concept of the “disease ecosystem” breaks down traditional barriers between basic and clinical research, and across disciplines. This framework integrates findings from microenvironment, microbiota, metabolic regulation, neuro-immune crosstalk, and other dimensions into a unified model of analysis. Additionally, amid evolving global disease patterns and growing demands for precision medicine, clinical practice requires greater translational application of pathological discoveries. There is, therefore, an urgent need for an academic journal platform dedicated to highlighting frontier technologies, accelerating basic-clinical translation, and fostering robust multi-disciplinary collaboration. Such a journal would serve as a vital bridge connecting pathologists, clinicians, and technologists worldwide, accelerating the translation of innovative discovery to clinical impact. It is in this context that the launch of
Pathology Research is timely and essential.
Pathology Research is an international, peer-reviewed journal dedicated to publishing advances in experimental, translational and clinical pathology. Our mission is to pioneer a holistic understanding of disease as a dynamic ecosystem, integrating the study of microenvironment, microbiota, metabolite, nervous system, and pathophysiology. By fostering interdisciplinary collaboration among pathologists, clinicians, computer scientists, and biomedical researchers, the Journal covers a broad spectrum of pathology-related disciplines, including:
| Surgical and molecular pathology |
| Artificial intelligence in pathology |
| Spatial multi-omics and molecular genetics |
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