Breaking through tradition: A new study on the ¹²⁵I seeds implantation assisted by the puncture angle guidance device

Abstract

This study was conducted to compare the difference between the use of a puncture angle guide device assisted needle insertion and manual needle entry for the treatment of single metastatic lymph nodes above the thoracic entrance by ¹²⁵I seeds implantation, and explore the feasibility and safety of ¹²⁵I seeds implantation assisted by the puncture angle guide device. Twenty patients who underwent ¹²⁵I seeds implantation for the treatment of single metastatic lymph nodes above the thoracic entrance at Jiangsu Cancer Hospital from April 2023 to December 2024 were enrolled in this study, and they were randomly divided into two groups. In the Auxiliary group, the puncture angle guide device was used for ¹²⁵I seeds implantation, while in the Manual group, the needles were deployed only by hand for ¹²⁵I seeds implantation. The puncture time, the number of puncture needle adjustments, the number of CT scans, the number of implanted seeds, the dosimetry indicators, and the occurrence of complications were compared between the two groups, and the differences were statistically analyzed. Both groups successfully completed the ¹²⁵I seeds implantation. The needle deployment time, the number of puncture needle adjustments, and the number of CT scans in the Auxiliary group were less than those in the Manual group, and the difference was statistically significant (p <.05). There was no statistical difference in the dosimetry parameters, the difference in dosimetry parameters, and the incidence of complications (Bleeding, pneumothorax) between the two groups before or after the operation (p >.05). The puncture angle guide device assisted ¹²⁵I seeds implantation is safe and feasible. Compared with the manual deployment of needles, the puncture time, the number of puncture needle adjustments, and the number of intraoperative CT scans are significantly reduced, which can be used in clinical applications.

Keywords

angle guidance / feasibility / metastatic lymph node / radioactive seed implantation

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2026 The Author(s). Precision Medical Sciences published by John Wiley & Sons Australia, Ltd on behalf of Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital.