Application of nurse-led CINV management scheme based on risk assessment in breast cancer patients

Abstract

Background: As one of the common adverse reactions after chemotherapy in breast cancer patients, chemotherapy-induced nausea and vomiting (CINV) seriously affects the quality of life of breast cancer patients.

Objective: To explore the application effect of nurse-led CINV management scheme based on risk assessment in breast cancer patients.

Methods: The researchers selected 90 breast cancer patients who received chemotherapy at Jiangsu Cancer Hospital from June 1, 2022, to June 1, 2023. The patients were divided into control group and intervention group. The control group implemented the routine nursing mode, and the intervention group implemented the nurse-led intervention program based on risk assessment. On this basis, the intervention group applied the symptom management theory to the construction of intervention strategy to compare the CINV situation, quality of life, and psychological distress level between the two groups.

Results: The frequency of vomiting and the degree of nausea in the delayed stage were lower in the intervention group than in the control group, and the difference was statistically significant (p<.05). The life function index of nausea and vomiting in acute stage and delayed stage was higher in the intervention group than in the control group, and the differences were statistically significant (p<.05). The psychological pain scores of the two groups in the acute stage and the delayed stage were lower in the intervention group than in the control group, and the differences were statistically significant (p<.05).

Conclusion: Nurse-led CINV management scheme based on risk assessment can effectively reduce the frequency of vomiting, reduce the degree of nausea, improve the quality of life, and alleviate psychological pain in breast cancer patients.

Keywords

breast cancer / CINV / risk assessment / symptom management

References

[1] Sung H, Ferlay J, Siegel RL. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71(3): 209-249.

[2] Smolarz B, Nowak AZ, Romanowicz H. Breast cancer-epidemiology, classification pathogenesis and treatment (review of literature). Cancers. 2022; 14(10): 2569.

[3] National Comprehensive Cancer Network. Antiemesis. Available at: https//www.nccn.org

[4] Gala D, Wright HH, Zigori B, Marshall S, Crichton M. Dietary strategies for chemotherapy-induced nausea and vomiting: a systematic review. Clin Nutr. 2022; 41(10): 2147-2155.

[5] Patel P, Robinson PD, Wahib N, et al. Interventions for the prevention of acute phase chemotherapy-induced nausea and vomiting in adult and pediatric patients: a systematic review and meta-analysis. Support Care Cancer. 2022; 30(11): 8855-8869.

[6] Wazqar DY, Thabet HA, Safwat AM. A quasi-experimental study of the effect of ginger tea on preventing nausea and vomiting in patients with gynecological cancers receiving cisplatin-based regimens. Cancer Nurs. 2021; 44(6): E513-e519.

[7] Gupta K, Walton R, Kataria SP. Chemotherapy-induced nausea and vomiting: pathogenesis, recommendations, and new trends. Cancer Treat Res Commun. 2021; 26: 100278.

[8] Baileys K, Mcmullen L, Lubejko B, et al. Nurse navigator Core competencies: an update to reflect the evolution of the role. Clin J Oncol Nurs. 2018; 22(3): 272-281.

[9] Croisier E, Brown T, Bauer J. The efficacy of dietary fiber in managing gastrointestinal toxicity symptoms in patients with gynecologic cancers undergoing pelvic radiotherapy: a systematic review. J Acad Nutr Diet. 2021; 121(2): 261-277.e2.

[10] Fabbro M, Jacot W, Jarlier M, et al. Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: a feasibility study. Cancer Rep. 2023; 6(1): e1732.

[11] Cheng P, Wang X. The effects of acupuncture at different intervention time points on nausea and vomiting caused by cisplatin chemotherapy in patients with lung cancer. Int J Clin Exp Med. 2020; 13(10): 7965-7971.

[12] Altuntaş D, Dalgiç A. The effects of acupressure in the prevention of nausea and vomiting related to chemotherapy in children: a randomized double-blinded placebo-controlled study. Randomized Controlled Trial. 2022; 39(6): 386-395.

[13] Toniolo J, Delaide V, Beloni P. Effectiveness of inhaled aromatherapy on chemotherapy-induced nausea and vomiting: a systematic review. J Altern Complement Med. 2021; 27(12): 1058-1069.

[14] Pozhhan M, Sobhani S, Rasouli AS, Tohidinezhad F. The effect of music therapy on chemotherapy-induced nausea and vomiting in women with breast cancer. Indian J Cancer. 2023; 60(1): 87-91.

[15] Wong CL, Li CK, Choi KC, et al. Effects of immersive virtual reality for managing anxiety, nausea and vomiting among paediatric cancer patients receiving their first chemotherapy: an exploratory randomised controlled trial. Eur J Oncol Nurs. 2022; 61: 102233.

[16] Cope DG. Clinical updates in nausea and vomiting. Semin Oncol Nurs. 2022; 38(1): 151249.

[17] Linder L. Analysis of the UCSF symptom management theory: implications for pediatric oncology nursing. J Pediatr Oncol Nurs. 2010; 27(6): 316-324.

[18] Dodd M, Janson S, Facione N, et al. Advancing the science of symptom management. J Adv Nurs. 2001; 33(5): 668-676.

[19] Mathew A, Doorenbos AZ, Vincent C. Symptom management theory analysis, evaluation, and implications for caring for adults with cancer. Adv Nurs Sci. 2021; 44(3): E93-E112.

[20] Toledo G, Ochoa CY, Farias AJ. Religion and spirituality: their role in the psychosocial adjustment to breast cancer and subsequent symptom management of adjuvant endocrine therapy. Support Care Cancer. 2021; 29(6): 3017-3024.

[21] Zhu BP. Effect of dietary nursing intervention on nausea and vomiting in patients with gastric cancer receiving chemotherapy. Chin J Health Standards Manag. 2018; 02: 185-186.

[22] Brearley SG, Clements CV, Molassiotis A. A review of patient self-report tools for chemotherapy-induced nausea and vomiting. Support Care Cancer. 2008; 16(11): 1213-1229.

[23] Li XF, Liu W, Qin Y. Reliability and validity of MASCC evaluation for antiemesis. Chin J Mod Nurs. 2016; 19: 2669-2673.

[24] Dranitsaris G, Molassiotis A, Clemons M, et al. The development of a prediction tool to identify cancer patients at high risk for chemotherapy-induced nausea and vomiting. Ann Oncol. 2017; 28(6): 1260-1267.

[25] Martin AR, Pearson JD, Cai B, Elmer M, Horgan K, Lindley C. Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ daily lives: a modified version of the functional living index-emesis (FLIE) with 5-day recall. Support Care Cancer. 2003; 11(8): 522-527.

[26] Roth AJ, Kornblith AB, Batel-Copel L. Peabody E, Scher HI, Holland JC. Rapid screening for psychologic distress in men with prostate carcinoma: a pilot study. Cancer. 1998; 82(10): 1904-1908.

[27] Samami E, Shahhosseini Z, Hamzehgardeshi Z, Elyasi F. Psychological interventions in chemotherapy-induced nausea and vomiting in women with breast cancer: a systematic review. Iran J Med Sci. 2022; 47(2): 95-106.

[28] De Lima D, Bezerra A, Matias De Sousa I, et al. Early nutritional intervention does not prevent long-term adverse events in women with breast cancer: a pilot study. Clin Nutr ESPEN. 2023; 53: 268-273.

[29] Park S, Sato Y, Takita Y, et al. Mindfulness-based cognitive therapy for psychological distress, fear of cancer recurrence, fatigue, spiritual well-being, and quality of life in patients with breast cancer-a randomized controlled trial. J Pain Symptom Manage. 2020; 60(2): 381-389.

[30] Shen Y, Zhang GJ, Yun BQ, et al. Longitudinal study on psychological distress level and its influencing factors in patients with breast cancer. Chin J Nurs Manag. 2018; 5: 617-622.

RIGHTS & PERMISSIONS

2024 The Author(s). Precision Medical Sciences published by John Wiley & Sons Australia, Ltd on behalf of Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital.