Design and simulation of ultrasensitive nano-biosensor based on OFPC

Abstract

We designed and simulated a nano-biosensor to work in wet chemical optical processes for the determination and analysis of gaseous or liquid media. For this purpose, the optical properties of materials have been studied, and by creating the relationship between the refractive index of materials and other optical parameters, the measurement process was carried out. In this work, an optical filter based on the photonic crystal (OFPC) was used. By creating an active environment for the interaction between the substance and electromagnetic light, a situation to measure the properties of available substances in that active environment could be provided. Considering that the defect created in the OFPC may cause disruption in its operation, so the volume of the environment should be limited. Creation of defects in the structure of the nano-biosensors can increase the accuracy and quality of measurements; finally by rearranging the created defects, the output will be placed in the appropriate scope. The accuracy is increased by applying the finite difference time domain (FDTD) modeling approach in order to analyze the wave equations governing the structure of the photonics crystal.

Keywords

Nano-biosensor / OFPC / Q-factor / sensitivity / FDTD

References

[1] Olyaee S, Dehghani A A. High resolution and wide dynamic range pressure sensor based on two-dimensional photonic crystal. Photonic Sensors, 2012, 2(1): 92-96.

[2] Rostami A, Banaei H A, Nazari F, Bahrami A. An ultra-compact photonic crystal wavelength division demultiplexer using resonance cavities in a modified Y-branch structure. Optik — International Journal for Light and Electron Optics, 2011, 122(16): 1481-1485.

[3] Hsiao F, Lee C. Novel biosensor based on photonic crystal nano-ring resonator. Procedia Chemistry, 2009, 1(1): 417-420.

[4] Kovacs A, Malisauskaite A, Ivanov A, Mescheder U, Wittig R. Optical sensing and analysis system based on porous layers. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Germany, October 27–31, 2013

[5] Olyaee S, Azizi M. Micro displacement sensor based on high sensitivity photonic crystal. Photonic Sensors, 2014, 4(3): 220-224.

[6] Levy O, Steinberg B Z, Nathan M, Boag A. Ultrasensitive displacement sensing using photonic crystal waveguides. Applied Physics Letters, 2005, 86(10): 104102-104104.

[7] Manoharan K. Design and analysis of high-Q, amorphousmicroring resonator sensors for gaseous and biological species detection, 2009, America: Russ College of Engineering and Technology of Ohio University

[8] Vengsarkar A M, Lemaire P J, Judkins J B, Bhatia V, Erdogan T, Sipe J E. Long period gratings as band-rejection filters. Journal of Lightwave Technology, 1996, 14(1): 58-64.

[9] Kalli K, Allsop T, Zhou K, Smith G, Komodromos M, Webb D, . Sensing properties of femtosecond laser-inscribed long period gratings in photonic crystal fiber. Photonic Sensors, 2011, 1(3): 228-233.

[10] Qiu M. Effective index method for hetero structure-slab-waveguide-based-two-dimensional photonic crystals. Applied Physics Letters, 2002, 81(7): 1163-1165.

[11] Sun J, Chan C C. Photonic bandgap fiber for refractive index measurement. Sensors and Actuators B: Chemical, 2007, 128(1): 46-50.

[12] Kwon S H, Sünner T, Kamp M, Forchel A. Optimization of photonic crystal cavity for chemical sensing. Optics Express, 2008, 16(16): 11709-11717.

[13] Hallynck E, Biensman P. Photonic crystal biosensor based on angular spectrum analysis. Optics Express, 2010, 18(17): 18164-18170.

[14] Yang D, Tian H, Ji Y. Micro-displacement sensor based on high-Q nanocavity in slot photonic crystal. Optical Engineering, 2011, 50(5): 544021-544026.

[15] Joannopoulos J D, Johnson S G, Winn J N, Meade R D. Photonic crystals molding the flow of light, 2007, Princeton: Princeton University Press

[16] Bhatia V. Applications of long-period gratings to single and multi-parameter sensing. Optics Express, 1999, 4(11): 457-466.

[17] Toccafondo V, García-Rupérez J, Bañuls M J, Griol A, García-Castelló J, Peransi-Llopis S, . DNA detection using a photonic crystal waveguide sensor. Advanced Photonics and Renewable Energy, 2010

[18] Moutzouris K, Papamichael M, Betsis S C, Stavrakas I, Hloupis G, Triantis D. Refractive, dispersive and thermo-optic properties of twelve organic solvents in the visible and near infrared. Applied Physics B, 2014, 116(3): 617-622.

[19] Foresi J S, Villeneuve P R, Ferrera J, Thoen E R, Steinmeyer G, Fan S, . Photonic-bandgapmicrocavities in optical waveguides. Nature, 1997, 390, 143-145.