When Vitamin Supplementation May Cause More Harm Than Good—An Avoidable Case of Intracranial Hypertension

Kellie Kum Foong Yip; Sameerah Muhammad Samir; Sudipta Roy Chowdhury

doi:10.1002/pdi3.70046

Pediatric Discovery ›› 2026, Vol. 4 ›› Issue (1) :e70046 DOI: 10.1002/pdi3.70046

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When Vitamin Supplementation May Cause More Harm Than Good—An Avoidable Case of Intracranial Hypertension

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Kellie Kum Foong Yip, Sameerah Muhammad Samir, Sudipta Roy Chowdhury. When Vitamin Supplementation May Cause More Harm Than Good—An Avoidable Case of Intracranial Hypertension. Pediatric Discovery, 2026, 4 (1) : e70046 DOI:10.1002/pdi3.70046

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References

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[1]	K. Kilic, J. J. Korsbæk, R. H. Jensen, and V. V. Cvetkovic, “Diagnosis of Idiopathic Intracranial Hypertension—The Importance of Excluding Secondary Causes: A Systematic Review,” Cephalalgia 42, no. 6 (2022): 524–541.

[2]	A. Malem, T. Sheth, and B. Muthusamy, “Paediatric Idiopathic Intracranial Hypertension (IIH): A Review,” Life 11, no. 7 (2021): 632.

[3]	A. J. Degnan and L. M. Levy, “Pseudotumor Cerebri: Brief Review of Clinical Syndrome and Imaging Findings,” American Journal of Neuroradiology 32, no. 11 (2011): 1986–1993.

[4]	K. T. Gondi, K. S. Chen, and S. M. Gratton, “Asymptomatic Versus Symptomatic Idiopathic Intracranial Hypertension in Children,” Journal of Child Neurology 34, no. 12 (2019): 751–756.

[5]	A. Nitzan-Luques, Y. Bulkowstein, N. Barnoy, A. Aran, S. Reif, and T. Gilboa, “Improving Pediatric Idiopathic Intracranial Hypertension Care: A Retrospective Cohort Study,” Scientific Reports 12, no. 1 (2022): 19218.

[6]	J. Genizi, E. Lahat, N. Zelnik, M. Mahajnah, S. Ravid, and E. Shahar, “Childhood-Onset Idiopathic Intracranial Hypertension: Relation of Sex and Obesity,” Pediatric Neurology 36, no. 4 (2007): 247–249.

[7]	M. G. Tan, B. Worley, W. B. Kim, M. ten Hove, and J. Beecker, “Drug-Induced Intracranial Hypertension: A Systematic Review and Critical Assessment of Drug-Induced Causes,” American Journal of Clinical Dermatology 21, no. 2 (2020): 163–172.

[8]	G. Q. Sharieff and K. Hanten, “Pseudotumor Cerebri and Hypercalcemia Resulting From Vitamin a Toxicity,” Annals of Emergency Medicine 27, no. 4 (1996): 518–521.

[9]	M. Lagacé, M. Oskoui, and K. Myers, “Not a Benign Vitamin: Infant With Vitamin a Toxicity and Acute Intracranial Hypertension,” Canadian Journal of Neurological Sciences (Le Journal Canadien des Sciences Neurologiques) 51, no. 2 (2024): 308–309.

[10]	F. W. Fraunfelder, F. T. Fraunfelder, and J. J. Corbett, “Isotretinoin-Associated Intracranial Hypertension,” Ophthalmology 111, no. 6 (2004): 1248–1250.

[11]	J. Libien, M. Kupersmith, W. Blaner, et al., “Role of Vitamin a Metabolism in IIH: Results From the Idiopathic Intracranial Hypertension Treatment Trial,” Journal of the Neurological Sciences 372 (2017): 78–84.

[12]	H. Stiebel-Kalish, S. Eyal, and I. Steiner, “The Role of Aquaporin-1 in Idiopathic and Drug-Induced Intracranial Hypertension,” Medical Hypotheses 81, no. 6 (2013): 1059–1062.

[13]	K. L. Penniston and S. A. Tanumihardjo, “The Acute and Chronic Toxic Effects of Vitamin A,” American Journal of Clinical Nutrition 83, no. 2 (2006): 191–201.

[14]	A. Tabassi, A. H. Salmasi, and M. Jalali, “Serum and CSF Vitamin a Concentrations in Idiopathic Intracranial Hypertension,” Neurology 64, no. 11 (2005): 1893–1896.

[15]	C. Schmitt, B. Domangé, R. Torrents, L. de Haro, and N. Simon, “Hypervitaminosis a Following the Ingestion of Fish Liver: Report on 3 Cases From the Poison Control Center in Marseille,” Wilderness and Environmental Medicine 31, no. 4 (2020): 454–456.

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2026 The Author(s). Pediatric Discovery published by John Wiley & Sons Australia, Ltd on behalf of Children's Hospital of Chongqing Medical University.