Application of metagenomic next-generation sequencing with brain tissue biopsy for diagnosing intracranial lesions in people with HIV

Ethics statement

This study was approved by the Ethics Committee of the First Affiliated Hospital of the Medical College of Zhejiang University (No. IIT20230188B) and complies with the principles of the Declaration of Helsinki. All data were analysed anonymously.

Acknowledgements

This study was supported by grants from the National Key R&D Program of China (Grants No. 2022YFC2305202, 2021YFC2301900-2021YFC2301901). We thank the study participants, and their friends and family members.

Author contributions

Ye Xiong (Conceptualization, Data curation, Methodology, Project administration, Writing—original draft), Dairong Xiang (Conceptualization, Investigation, Project administration, Visualization), Xiaotang Zhou (Conceptualization, Investigation, Methodology, Project administration, Validation, Visualization), Ying Huang (Data curation, Project administration, Resources), Jean-Pierre Routy (Supervision, Visualization, Writing—review & editing), and Biao Zhu (Conceptualization, Funding acquisition, Supervision, Visualization, Writing—review & editing)

Conflict of interest

None declared.

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