Autologous fat transplantation technology: traditional therapies and emerging applications

Abstract

In recent years, autologous fat transplantation technology has been widely applied in tissue repair and regenerative medicine. Autologous fat grafts offer several advantages: they are easy to harvest, possess favorable biocompatibility and excellent tissue integration capacity, and serve as an abundant source of stem cells. Refined techniques for fat extraction, processing, and transplantation, not only can morphological improvements be achieved, but the regeneration and functional recovery of damaged tissues can also be promoted. This review summarizes the wide-ranging clinical applications of fat grafting, covering tissue reconstruction, alopecia management, local drug delivery, and other novel indications. Combined with multidisciplinary strategies and advanced technologies, this technique can better satisfy the structural and functional requirements of recipient sites. Autologous fat grafting is evolving toward personalized and precise therapeutic regimens, providing patients with more diverse and effective treatment options. In the future, therapies based on adipose tissue are expected to become more tissue-specific and emerge as a new platform for regenerative medicine.

Keywords

Fat transplantation / ADSCs / regenerative medicine / clinical application / tissue engineering

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