Role of the extracellular matrix in skin aging and dedicated treatment - State of the art

Abstract

The extracellular matrix (ECM) occupies the space between cell and cell, and serves as a sort of intranet which connects the whole organism. Current research is focused on the ECM and, it is now possible to develop increasingly effective strategies for the prevention and treatment of degenerative diseases and even, cutaneous ageing. In fact, the most advanced anti-aging treatments are those that regenerate the ECM, which is now regarded as the main player in the physical support of, and exchange with and between cells of nutrients, cellular mediators and growth factors.

Keywords

Collagen / elastin / hyaluronic acid / extracellular matrix / matrisome

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