Protein & Cell >

2023 , Vol. 14 >Issue 2: 149 - 152

DOI: https://doi.org/10.1093/procel/pwac003

LETTER

RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes

  • Lili Yu , 1,2,3 ,
  • Lei Jiang 4 ,
  • Meng Wu 1 ,
  • Wenlong Dou 4 ,
  • Kaiyuan Ji 4 ,
  • Jianlong Zhou 4 ,
  • Jinchul Kim 5 ,
  • Yang Xu , 1
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  • 1. Department of Cardiology, Cardiovascular Key Lab of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
  • 2. Department of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
  • 3. Cancer Center, Zhejiang University, Hangzhou 310058, China
  • 4. School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China
  • 5. Ageing Research Center, Korea Research Institute of Bioscience and Biotechnology, Deajeon 34141, Korea
2321128@zju.edu.cn
xuyang2020@zju.edu.cn

Accepted date: 25 Mar 2022

Copyright

2022 The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.
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Cite this article

Lili Yu , Lei Jiang , Meng Wu , Wenlong Dou , Kaiyuan Ji , Jianlong Zhou , Jinchul Kim , Yang Xu . RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes[J]. Protein & Cell, 2023 , 14(2) : 149 -152 . DOI: 10.1093/procel/pwac003

References

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Molleston JM, Sabin LR, Moy RH et al. A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Genes Dev 2016;30:1658–1670.

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Yu L, Kim J, Jiang L et al. MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. Nat Communi 2020;11(1):708.

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Zapatka M, Borozan I, Brewer DS et al. The landscape of viral associations in human cancers. Nat Genetics 2020;52:320–330.

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