LETTER

Large-scale chemical screen identifies Gallic acid as a geroprotector for human stem cells

  • Hezhen Shan 1,11 ,
  • Lingling Geng 3,8 ,
  • Xiaoyu Jiang 1,7 ,
  • Moshi Song 1,7,9 ,
  • Jianxun Wang 11 ,
  • Zunpeng Liu 2,7 ,
  • Xiao Zhuo 4,5 ,
  • Zeming Wu 1,9 ,
  • Jianli Hu 4,7 ,
  • Zhejun Ji 2,6,9 ,
  • Si Wang 3,8 ,
  • Piu Chan 3 ,
  • Jing Qu , 2,6,7,9 ,
  • Weiqi Zhang , 4,5,6,7,10 ,
  • Guang-Hui Liu , 1,3,6,7,9
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  • 1. State Key Laboratory of Membrane Biology, Institute of Zoology Chinese Academy of Sciences, Beijing 100101, China
  • 2. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
  • 3. Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China
  • 4. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
  • 5. China National Center for Bioinformation, Beijing 100101, China
  • 6. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China
  • 7. University of Chinese Academy of Sciences, Beijing 100049, China
  • 8. Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • 9. Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China
  • 10. Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China
  • 11. School of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China

Accepted date: 30 Jul 2021

Published date: 15 Jul 2022

Copyright

2021 The Author(s)

Cite this article

Hezhen Shan , Lingling Geng , Xiaoyu Jiang , Moshi Song , Jianxun Wang , Zunpeng Liu , Xiao Zhuo , Zeming Wu , Jianli Hu , Zhejun Ji , Si Wang , Piu Chan , Jing Qu , Weiqi Zhang , Guang-Hui Liu . Large-scale chemical screen identifies Gallic acid as a geroprotector for human stem cells[J]. Protein & Cell, 2022 , 13(7) : 532 -539 . DOI: 10.1007/s13238-021-00872-5

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