Binding to m6A RNA promotes YTHDF2-mediated phase separation
Published date: 15 Apr 2020
Copyright
Jiahua Wang , Liyong Wang , Jianbo Diao , Yujiang Geno Shi , Yang Shi , Honghui Ma , Hongjie Shen . Binding to m6A RNA promotes YTHDF2-mediated phase separation[J]. Protein & Cell, 2020 , 11(4) : 304 -307 . DOI: 10.1007/s13238-019-00660-2
1 |
Fu Y, Zhuang X (2019) m6A-binding YTHDF proteins promote stress granule formation by modulating phase separation of stress granule proteins. bioRxiv.
|
2 |
Gao Y, Pei G, Li D, Li R, Shao Y, Zhang QC, Li P (2019) Multivalent m(6)A motifs promote phase separation of YTHDF proteins. Cell Res 29:767–769
|
3 |
Hazra D, Chapat C, Graille M (2019) m(6)A mRNA destiny: chained to the rhYTHm by the YTH-containing proteins. Genes 10:49
|
4 |
Kroschwald S, Maharana S, Simon A (2017) Hexanediol: a chemical probe to investigate the material properties of membrane-less compartments. Matters 3:e161462902
|
5 |
Li A, Chen YS, Ping XL, Yang X, Xiao W, Yang Y, Sun HY, Zhu Q, Baidya P, Wang X et al (2017) Cytoplasmic m(6)A reader YTHDF3 promotes mRNA translation. Cell Res 27:444–447
|
6 |
Li F, Zhao D, Wu J, Shi Y (2014) Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition. Cell Res 24:1490–1492
|
7 |
Ries RJ, Zaccara S, Klein P, Olarerin-George A, Namkoong S, Pickering BF, Patil DP, Kwak H, Lee JH, Jaffrey SR (2019) m(6)A enhances the phase separation potential of mRNA. Nature 571:424–428
|
8 |
Sabari BR, Dall’Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC et al (2018) Coactivator condensation at super-enhancers links phase separation and gene control. Science 361:eaar3958
|
9 |
Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu PJ, Liu C, He C (2017) YTHDF3 facilitates translation and decay of N(6)-methyladenosine-modified RNA. Cell Res 27:315–328
|
10 |
Shi H, Wei J, He C (2019) Where, when, and how: contextdependent functions of RNA methylation writers, readers, and erasers. Mol Cell 74:640–650
|
11 |
Standart N, Weil D (2018) P-bodies: cytosolic droplets for coordinated mRNA storage. Trends Genet 34:612–626
|
12 |
Strom AR, Emelyanov AV, Mir M, Fyodorov DV, Darzacq X, Karpen GH (2017) Phase separation drives heterochromatin domain formation. Nature 547:241–245
|
13 |
Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han D, Fu Y, Parisien M, Dai Q, Jia G
|
14 |
Wang X, Zhao BS, Roundtree IA, Lu Z, Han D, Ma H, Weng X, Chen K, Shi H, He C (2015) N(6)-methyladenosine modulates messenger RNA translation efficiency. Cell 161:1388–1399
|
/
〈 | 〉 |