LETTER

Neonatal lethality and recycling defect of transferrin receptor in mice with Syntaxin12/13 disruption

  • Fang Li 1,2 ,
  • Chun-Feng Liu 1,2,4 ,
  • Yin-Zhen Xu 1,2 ,
  • Yi-Lin Guo 3 ,
  • Shu-Wen Xue 3 ,
  • Xiang-Dong Kong 3 ,
  • Hai-bing Zhang 1,2 ,
  • Yan Zhang 1,2 ,
  • Jian-Sheng Kang , 1,2,3
Expand
  • 1. CAS Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
  • 2. University of Chinese Academy of Sciences, Beijing 100049, China
  • 3. The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • 4. Technical Center for Animal, Plant and Food Inspection and Quarantine, Shanghai Entry-Exit Inspection and Quarantine Bureau, Shanghai 20013, China

Published date: 31 Jan 2019

Copyright

2018 The Author(s) 2018. This article is an open access publication

Cite this article

Fang Li , Chun-Feng Liu , Yin-Zhen Xu , Yi-Lin Guo , Shu-Wen Xue , Xiang-Dong Kong , Hai-bing Zhang , Yan Zhang , Jian-Sheng Kang . Neonatal lethality and recycling defect of transferrin receptor in mice with Syntaxin12/13 disruption[J]. Protein & Cell, 2019 , 10(1) : 67 -71 . DOI: 10.1007/s13238-018-0519-6

1
Aisen P (2001) Chemistry and biology of eukaryotic iron metabolism. Int J Biochem Cell Biol 33:940–959

DOI

2
Andrews NC (2008) Forging a field: the golden age of iron biology. Blood 112:219–230

DOI

3
Bock JB, Matern HT, Peden AA, Scheller RH (2001) A genomic perspective on membrane compartment organization. Nature 409:839–841

DOI

4
Chen C, Garcia-Santos D, Ishikawa Y (2013) Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab 17:343–352

DOI

5
Gunshin H, Fujiwara Y, Custodio AO (2005) Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J Clin Invest 115:1258–1266

DOI

6
Hong W (2005) SNAREs and traffic. Biochim Biophys Acta BBA 1744:120–144

DOI

7
Levy JE, Jin O, Fujiwara Y (1999) Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet 21:396–399

DOI

8
Lim JE, Jin O, Bennett C (2005) A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat Genet 37:1270–1273

DOI

9
Lorenz L, Arand J, Büchner K (2015) Reticulocyte haemoglobin contentasamarkerof irondeficiency. ArchDisChild 00:F198–F202

DOI

10
Prekeris R, Klumperman J, Chen YA, Scheller RH (1998) Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes. J Cell Biol 143:957–971

DOI

11
Prekeris R, Foletti DL, Scheller RH (1999) Dynamics of tubulovesicular recycling endosomes in hippocampal neurons. J Neurosci 19:10324–10337

DOI

12
Sheftel AD, Zhang A-S, Brown C (2007) Direct interorganellar transferof ironfromendosometomitochondrion. lood 10:125–132

13
Südhof TC, Rothman JE (2009) Membrane fusion: grappling with SNARE and SM proteins. Science 323:474–477

DOI

14
Tang BL, Tan AEH, Lim LK (1998) Syntaxin 12, a member of the syntaxin family localized to the endosome. J Biol Chem 273:6944–6950

DOI

15
Zhu D, Xie L, Kang Y (2017) Syntaxin 2 acts as inhibitory SNARE for insulin granule exocytosis. Diabetes 66:948–959

DOI

Outlines

/