mTORC1 signaling in hepatic lipid metabolism
Received date: 02 Mar 2017
Accepted date: 04 Apr 2017
Published date: 22 Mar 2018
Copyright
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and physiological processes in different organs or tissues. Dysregulation of mTOR signaling has been implicated in many human diseases including obesity, diabetes, cancer, fatty liver diseases, and neuronal disorders. Here we review recent progress in understanding how mTORC1 (mTOR complex 1) signaling regulates lipid metabolism in the liver.
Key words: mTOR; mTORC1; lipogenesis; lipophagy
Jinbo Han , Yiguo Wang . mTORC1 signaling in hepatic lipid metabolism[J]. Protein & Cell, 2018 , 9(2) : 145 -151 . DOI: 10.1007/s13238-017-0409-3
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