LETTER

Targeted disruption of Rab10 causes early embryonic lethality

  • Pingping Lv 1,2 ,
  • Yi Sheng 1,3 ,
  • Zhenao Zhao 4 ,
  • Wei Zhao 1,2 ,
  • Lusheng Gu 1,3 ,
  • Tao Xu , 1 ,
  • Eli Song , 1
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  • 1. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
  • 2. University of Chinese Academy of Sciences, Beijing 100049, China
  • 3. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China
  • 4. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

Published date: 11 Jun 2015

Copyright

2014 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cite this article

Pingping Lv , Yi Sheng , Zhenao Zhao , Wei Zhao , Lusheng Gu , Tao Xu , Eli Song . Targeted disruption of Rab10 causes early embryonic lethality[J]. Protein & Cell, 2015 , 6(6) : 463 -467 . DOI: 10.1007/s13238-015-0150-8

1
Babbey CM, Ahktar N, Wang E, Chen CCH, Grant BD, Dunn KW (2006) Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells. Mol Biol Cell17: 3156-3175

DOI

2
Chen CC, Schweinsberg PJ, Vashist S, Mareiniss DP, Lambie EJ, Grant BD (2006) RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine. Mol Biol Cell17: 1286-1297

DOI

3
Chen Y, Wang Y, Zhang J, Deng Y, Jiang L, Song E, Wu XS, Hammer JA, Xu T, Lippincott-Schwartz J (2012) Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol198: 545-560

DOI

4
Chen S, Li L, Li J, Liu B, Zhu X, Zheng L, Zhang R, Xu T (2014) SEC-10 and RAB-10 coordinate basolateral recycling of clathrinindependent cargo through endosomal tubules in Caenorhabditis elegans. Proc Natl Acad Sci USA111: 15432-15437

DOI

5
Fürthauer M, González-Gaitán M (2009) Endocytic regulation of notch signalling during development. Traffic10: 792-802

DOI

6
Furthauer M, Gonzalez-Gaitan M (2009) Tales of 1001 functions: the multiple roles of membrane trafficking in development. Traffic10: 781-782

DOI

7
Kolotuev I, Apaydin A, Labouesse M (2009) Secretion of Hedgehogrelated peptides and WNT during caenorhabditis elegans development. Traffic10: 803-810

DOI

8
Lebreton S, Boissel L, Moreau J (2003) Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the Ras signalling pathway. J Cell Sci116: 4651-4662

DOI

9
Lerner DW, McCoy D, Isabella AJ, Mahowald AP, Gerlach GF, Chaudhry TA, Horne-Badovinac S (2013) A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis. Dev Cell24: 159-168

DOI

10
Lučin P, Mahmutefendić H, Blagojević Zagorac G, Ilić Tomaš M (2014) Cytomegalovirus immune evasion by perturbation of endosomal trafficking. Cell Mol Immunol12: 154-169

DOI

11
Richter S, Voss U, Jurgens G (2009) Post-Golgi traffic in plants. Traffic10: 819-828

DOI

12
Stenmark H (2009) Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Bio10: 513-525

DOI

13
Ulrich F, Heisenberg CP (2009) Trafficking and cell migration. Traffic10: 811-818

DOI

14
Xu XH, Deng CY, Liu Y, He M, Peng J, Wang T, Yuan L, Zheng ZS, Blackshear PJ, Luo ZG (2014) MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development. Cell Res24: 576-594

DOI

15
Zerial M, McBride H (2001) Rab proteins as membrane organizers. Nat Rev Mol Cell Bio2: 107-117

DOI

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