IDDoR: a novel reporter mouse system for simultaneous and quantitative in vivo analysis of both DNA double-strand break repair pathways
Yu Chen, Zhen Cui, Zhixi Chen, Ying Jiang, Zhiyong Mao
IDDoR: a novel reporter mouse system for simultaneous and quantitative in vivo analysis of both DNA double-strand break repair pathways
[1] |
Bennardo N, Cheng A, Huang N et al. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet 2008; 4:e1000110.
CrossRef
Google scholar
|
[2] |
Bindra RS, Goglia AG, Jasin M et al. Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells. Nucleic Acids Res 2013;41:e115.
CrossRef
Google scholar
|
[3] |
Certo MT, Ryu BY, Annis JE et al. Tracking genome engineering outcome at individual DNA breakpoints. Nat Methods 2011;8:671–U102.
CrossRef
Google scholar
|
[4] |
Chen Y, Zhang HP, Xu Z et al. A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. Nucleic Acids Res 2019; 47: 8563–8580.
CrossRef
Google scholar
|
[5] |
Gomez-Cabello D, Jimeno S, Fernandez-Avila MJ et al. New tools to study DNA double-strand break repair pathway choice. PLoS One 2013;8:e77206.
CrossRef
Google scholar
|
[6] |
Hochedlinger K, Yamada Y, Beard C et al. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 2005;121:465–477.
CrossRef
Google scholar
|
[7] |
Kass EM, Helgadottir HR, Chen CC et al. Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proc Natl Acad Sci U S A 2013;110:5564–5569.
CrossRef
Google scholar
|
[8] |
Kass EM, Lim PX, Helgadottir HR et al. Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation. Nat Commun 2016;7:1–10.
CrossRef
Google scholar
|
[9] |
Mao ZY, Bozzella M, Seluanov A et al. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair 2008;7:1765–1771.
CrossRef
Google scholar
|
[10] |
Mao ZY, Tian X, Van Meter M et al. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proc Natl Acad Sci U S A 2012;109:11800–11805.
CrossRef
Google scholar
|
[11] |
Pierce AJ, Johnson RD, Thompson LH et al. XRCC3 promotes homology- directed repair of DNA damage in mammalian cells. Genes Dev 1999;13:2633–2638.
CrossRef
Google scholar
|
[12] |
Seluanov A, Mittelman D, Pereira-Smith OM et al. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proc Natl Acad Sci U S A 2004;101: 7624–7629.
CrossRef
Google scholar
|
[13] |
Tye KM, Mirzabekov JJ, Warden MR et al. Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature 2013;493: 537–541.
CrossRef
Google scholar
|
[14] |
Vaidya A, Mao ZY, Tian X et al. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. PLoS Genet 2014;10:e1004511.
CrossRef
Google scholar
|
[15] |
Wang C, Tang H, Geng A et al. Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors. Proc Natl Acad Sci U S A 2020;117: 26356–26365.
CrossRef
Google scholar
|
/
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