FTO stabilizes MIS12 and counteracts senescence

Sheng Zhang; Zeming Wu; Yue Shi; Si Wang; Jie Ren; Zihui Yu; Daoyuan Huang; Kaowen Yan; Yifang He; Xiaoqian Liu; Qianzhao Ji; Beibei Liu; Zunpeng Liu; Jing Qu; Guang-Hui Liu; Weimin Ci; Xiaoqun Wang; Weiqi Zhang

doi:10.1007/s13238-022-00914-6

Protein Cell ›› 2022, Vol. 13 ›› Issue (12) : 954 -960. DOI: 10.1007/s13238-022-00914-6

LETTER

FTO stabilizes MIS12 and counteracts senescence

Sheng Zhang ¹^,²^,³
, Zeming Wu ²^,⁴^,⁵
, Yue Shi ⁶^,⁷
, Si Wang ⁸^,⁹^,¹⁰
, Jie Ren ³^,⁴^,⁶^,⁷^,¹¹
, Zihui Yu ³^,⁶^,⁷
, Daoyuan Huang ⁸
, Kaowen Yan ²^,⁴^,⁵
, Yifang He ²^,³^,⁴^,⁵
, Xiaoqian Liu ⁴^,⁵^,¹²
, Qianzhao Ji ²^,³
, Beibei Liu ⁶^,⁷
, Zunpeng Liu ³^,¹²
, Jing Qu ³^,⁴^,⁵^,¹²
, Guang-Hui Liu ²^,³^,⁴^,⁵^,⁸^,⁹^,^†
, Weimin Ci ³^,⁴^,⁶^,⁷^,^†
, Xiaoqun Wang ¹^,³^,⁴^,¹³^,^†
, Weiqi Zhang ³^,⁴^,⁶^,⁷^,^†

Author information +

¹. State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Brain-Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

². State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

³. University of Chinese Academy of Sciences, Beijing 100049, China

⁴. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China

⁵. Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China

⁶. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China

⁷. China National Center for Bioinformation, Beijing 100101, China

⁸. Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

⁹. Aging Translational Medicine Center, International Center for Aging and Cancer, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

¹⁰. Chongqing Renji Hospital, University of Chinese Academy of Sciences, Chongqing 400062, China

¹¹. Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China

¹². State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

¹³. Beijing Institute for Brain Disorders, Beijing 100069, China

ghliu@ioz.ac.cn

ciwm@big.ac.cn

xiaoqunwang@ibp.ac.cn

zhangwq@big.ac.cn

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Sheng Zhang, Zeming Wu, Yue Shi, Si Wang, Jie Ren, Zihui Yu, Daoyuan Huang, Kaowen Yan, Yifang He, Xiaoqian Liu, Qianzhao Ji, Beibei Liu, Zunpeng Liu, Jing Qu, Guang-Hui Liu, Weimin Ci, Xiaoqun Wang, Weiqi Zhang. FTO stabilizes MIS12 and counteracts senescence. Protein Cell, 2022, 13(12): 954-960 DOI:10.1007/s13238-022-00914-6

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