Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine

References

[1] Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B (2011) Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature 470:95–100

[2] Huang J, Arsenault M, Kann M, Lopez-Mendez C, Saleh M, Wadowska D, Taglienti M, Ho J, Miao Y, Sims D (2013) The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn 242:790–799

[3] Kang HM, Huang S, Reidy K, Han SH, Chinga F, Susztak K (2016) Sox9-positive progenitor cells play a key role in renal tubule epithelial regeneration in mice. Cell Reports 14:861–871

[4] Kitamura S, Sakurai H, Makino H (2015) Single adult kidney stem/progenitor cells reconstitute three-dimensional nephron structures in vitro. stem Cells 33:774

[5] Kumar Sanjeev, Liu Jing, Pang Paul, Krautzberger A, Michaela (2015) Sox9 activation highlights a cellular pathway of renal repair in the acutely injured mammalian kidney. Cell Reports 12:1325–1338

[6] Lazzeri E, Ronconi E, Angelotti ML, Peired A, Mazzinghi B, Becherucci F, Conti S, Sansavini G, Sisti A, Ravaglia F (2015) Human urine-derived renal progenitors for personalized modeling of genetic kidney disorders. J Am Soc Nephrol 26:1961–1974

[7] Ma Q, Yu M, Dai X, Tao R, Fu Y, Liu W, Han Y, Wu Y, Yu C, Zhang T (2018) Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation. Protein Cell 9:267–282

[8] Maeshima A, Yamashita S, Nojima Y (2003) Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. J Am Soc Nephrol 14:3138–3146

[9] Oliveira Arcolino F, Tort Piella A, Papadimitriou E, Bussolati B, Antonie DJ, Murray P, van den Heuvel L, Levtchenko E (2015) Human urine as a noninvasive source of kidney cells. Stem Cells Int 2015:362562

[10] Park J, Shrestha R, Qiu C, Kondo A, Huang S, Werth M, Li M, Barasch J, Susztak K (2018) Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease. Science 360:758–763

[11] Rossi, R., Lichtner , M., Iori, F., Ermocida, A., Mascia, C., Mengoni, F., Sauzullo , I., Dini, D., Mastroianni, C.M., and Vullo , V. (2013). Dendritic cells in blood and urine samples from bladder cancer patients undergoing BCG immunotherapy. Arch Ital Urol Androl 85:157–163.

[12] Sagrinati C, Netti GS, Mazzinghi B, Lazzeri E, Liotta F, Frosali F, Ronconi E, Meini C, Gacci M, Squecco R (2006) Isolation and characterization of multipotent progenitor cells from the Bowman’s capsule of adult human kidneys. J Am Soc Nephrol 17:2443–2456

[13] Schutgens F, Rookmaaker MB, Margaritis T, Rios A, Ammerlaan C, Jansen J, Gijzen L, Vormann M, Vonk A, Viveen M (2019) Tubuloids derived from human adult kidney and urine for personalized disease modeling. Nat Biotechnol 37:303–313

[14] Wu H, Malone AF, Donnelly EL, Kirita Y, Uchimura K, Ramakrishnan SM, Gaut JP, Humphreys BD (2018) Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response. J Am Soc Nephrol 29:2069–2080

[15] Zuo W, Zhang T, Wu DZ, Guan SP, Liew AA, Yamamoto Y, Wang X, Lim SJ, Vincent M, Lessard M (2015) p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration. Nature 517:616–620

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