Structural insights into the activation initiation of full-length mGlu1
Jinyi Zhang, Lu Qu, Lijie Wu, Xiaomeng Tang, Feng Luo, Weixiu Xu, Yueming Xu, Zhi-Jie Liu, Tian Hua
Structural insights into the activation initiation of full-length mGlu1
[1] |
Bessis AS, Rondard P, Gaven F, Brabet I, Triballeau N, Prezeau L, Acher F, Pin JP (2002) Closure of the Venus flytrap module of mGlu8 receptor and the activation process: insights from mutations converting antagonists into agonists. Proc Natl Acad Sci USA 99:11097–11102
CrossRef
Google scholar
|
[2] |
Doumazane E, Scholler P, Fabre L, Zwier JM, Trinquet E, Pin JP, Rondard P (2013) Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors. Proc Natl Acad Sci USA 110:E1416–1425
CrossRef
Google scholar
|
[3] |
Huang S, Cao J, Jiang M, Labesse G, Liu J, Pin JP, Rondard P (2011) Interdomain movements in metabotropic glutamate receptor activation. Proc Natl Acad Sci USA 108:15480–15485
CrossRef
Google scholar
|
[4] |
Knoflach F, Mutel V, Jolidon S, Kew JN, Malherbe P, Vieira E, Wichmann J, Kemp JA (2001) Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site. Proc Natl Acad Sci USA 98:13402–13407
CrossRef
Google scholar
|
[5] |
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laeremans T, Steyaert J
CrossRef
Google scholar
|
[6] |
Kunishima N, Shimada Y, Tsuji Y, Sato T, Yamamoto M, Kumasaka T, Nakanishi S, Jingami H, Morikawa K (2000) Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature 407:971–977
CrossRef
Google scholar
|
[7] |
Muto T, Tsuchiya D, Morikawa K, Jingami H (2007) Structures of the extracellular regions of the group II/III metabotropic glutamate receptors. Proc Natl Acad Sci USA 104:3759–3764
CrossRef
Google scholar
|
[8] |
Nakanishi S, Masu M (1994) Molecular diversity and functions of glutamate receptors. Annu Rev Biophys Biomol Struct 23:319–348
CrossRef
Google scholar
|
[9] |
Pin JP, Bettler B (2016) Organization and functions of mGlu and GABAB receptor complexes. Nature 540:60–68
CrossRef
Google scholar
|
[10] |
Scheefhals N, MacGillavry HD (2018) Functional organization of postsynaptic glutamate receptors. Mol Cell Neurosci 91:82–94
CrossRef
Google scholar
|
[11] |
Schoepp DD, Jane DE, Monn JA (1999) Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38:1431–1476
CrossRef
Google scholar
|
[12] |
Stansley BJ, Conn PJ (2019) Neuropharmacological insight from allosteric modulation of mGlu receptors. Trends Pharmacol Sci 40:240–252
CrossRef
Google scholar
|
[13] |
Tateyama M, Abe H, Nakata H, Saito O, Kubo Y (2004) Ligandinduced rearrangement of the dimeric metabotropic glutamate receptor 1alpha. Nat Struct Mol Biol 11:637–642
CrossRef
Google scholar
|
[14] |
Tsuchiya D, Kunishima N, Kamiya N, Jingami H, Morikawa K (2002) Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc Natl Acad Sci USA 99:2660–2665
CrossRef
Google scholar
|
[15] |
Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V
CrossRef
Google scholar
|
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