Tongue as a first-line immune organ?
Jane Y. Wu
Tongue as a first-line immune organ?
[1] |
Camandola S, Mattson MP (2017) Toll-like receptor 4 mediates fat, sugar, and umami taste preference and food intake and body weight regulation. Obesity 25(7):1237–1245
CrossRef
Google scholar
|
[2] |
Cao X (2020) COVID-19: immunopathology and its implications for therapy. Nat Rev Immunol. https://doi.org/10.1038/s41577-020-0308-3
CrossRef
Google scholar
|
[3] |
Carey RM, Lee RJ (2019) Taste receptors in upper airway innate immunity. Nutrients 11(9):2017
CrossRef
Google scholar
|
[4] |
Cuburu N, Kweon MN, Song JH, Hervouet C, Luci C, Sun JB, Hofman P, Holmgren J, Anjuère F, Czerkinsky C (2007) Sublingual immunization induces broad-based systemic and mucosal immune responses in mice. Vaccine 25(51):8598–8610
CrossRef
Google scholar
|
[5] |
Czerkinsky C, Cuburu N, Kweon MN, Anjuere F, Holmgren J (2011) Sublingual vaccination. Hum Vaccin 7(1):110–114
CrossRef
Google scholar
|
[6] |
Freund JR, Mansfield CJ, Doghramji LJ, Adappa ND, Palmer JN, Kennedy DW, Reed DR, Jiang P, Lee RJ (2018) Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling. J Biol Chem 293(25):9824–9840
CrossRef
Google scholar
|
[7] |
Gondak RO, Alves DB, Silva LF, Mauad T, Vargas PA (2012) Depletion of Langerhans cells in the tongue from patients with advanced-stage acquired immune deficiency syndrome: relation to opportunistic infections. Histopathology 60(3):497–503
CrossRef
Google scholar
|
[8] |
Grassin-Delyle S, Salvator H, Mantov N, Abrial C, Brollo M, Faisy C, Naline E, Couderc LJ, Devillier P (2019) Bitter taste receptors (TAS2Rs) in human lung macrophages: receptor expression and inhibitory effects of TAS2R agonists. Front Physiol 10:1267
CrossRef
Google scholar
|
[9] |
Iemoli E, Borgonovo L, Fusi A, Magni C, Ricci ED, Rizzardini G, Piconi S (2016) Sublingual allergen immunotherapy in HIVpositive patients. Allergy 71(3):412–415
CrossRef
Google scholar
|
[10] |
Jones AT, Shen X, Walter KL, LaBranche CC, Wyatt LS, Tomaras GD, Montefiori DC, Moss B, Barouch DH, Clements JD
CrossRef
Google scholar
|
[11] |
Malki A, Fiedler J, Fricke K, Ballweg I, Pfaffl MW, Krautwurst D (2015) Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes. J Leukoc Biol 97:533–545
CrossRef
Google scholar
|
[12] |
McCluskie MJ, Brazolot Millan CL, Gramzinski RA, Robinson HL, Santoro JC, Fuller JT, Widera G, Haynes JR, Purcell RH, Davis HL (1999) Route and method of delivery of DNA vaccine influence immune responses in mice and non-human primates. Mol Med 5(5):287–300
CrossRef
Google scholar
|
[13] |
Orsmark-Pietras C, James A, Konradsen JR, Nordlund B, Soderhall C, Pulkkinen V, Daham K, Kupczyk M, Dahlén B, Kere J (2013) Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics. Eur Respir J 42:65–78
CrossRef
Google scholar
|
[14] |
Park A, Iwasaki A (2020) Type I and Type III interferons—induction, signaling, evasion, and application to combat COVID-19. Cell Host Microbe 27(6):870–878
CrossRef
Google scholar
|
[15] |
Roper SD, Chaudhari N (2017) Taste buds: cells, signals and synapses. Nat Rev Neurosci 18(8):485–497
CrossRef
Google scholar
|
[16] |
Scheiblhofer S, Thalhamer J, Weiss R (2018) DNA and mRNA vaccination against allergies. Pediatr Allergy Immunol 29(7):679–688
CrossRef
Google scholar
|
[17] |
Shaikh N, Rivera J, Hewlett BR, Stead RH, Zhu FG, Marshall JS (1997) Mast cell Fc epsilonRI expression in the rat intestinal mucosa and tongue is enhanced during Nippostrongylus brasiliensis infection and can be up-regulated by in vivo administration of IgE. J Immunol 158(8):3805–3812
|
[18] |
Thirion-Delalande C, Gervais F, Fisch C, Cuiné J, Baron-Bodo V, Moingeon P, Mascarell L (2017) Comparative analysis of the oral mucosae from rodents and non-rodents: application to the nonclinical evaluation of sublingual immunotherapy products. PLoS ONE 12(9):e0183398
CrossRef
Google scholar
|
/
〈 | 〉 |