DJ-1 is dispensable for human stem cell homeostasis

Fang Cheng; Si Wang; Moshi Song; Zunpeng Liu; Ping Liu; Lei Wang; Yanjiang Wang; Qian Zhao; Kaowen Yan; Piu Chan; Weiqi Zhang; Jing Qu; Guang-Hui Liu

doi:10.1007/s13238-019-00659-9

PDF(3328 KB)

Protein Cell ›› 2019, Vol. 10 ›› Issue (11) : 846-853. DOI: 10.1007/s13238-019-00659-9

LETTER

DJ-1 is dispensable for human stem cell homeostasis

Fang Cheng¹^,⁷ ,
Si Wang²^,⁴^,⁷ ,
Moshi Song²^,⁷^,⁸ ,
Zunpeng Liu³^,⁷ ,
Ping Liu¹^,⁷ ,
Lei Wang¹^,⁷ ,
Yanjiang Wang⁵ ,
Qian Zhao⁴ ,
Kaowen Yan² ,
Piu Chan⁴ ,
Weiqi Zhang⁴^,⁶^,⁷^,⁸ ,
Jing Qu³^,⁷^,⁸ ,
Guang-Hui Liu¹^,⁴^,⁷^,⁸^,⁹

Author information +

History +

Cite this article

EndNote

Ris (Procite)

Bibtex

Download citation ▾

Fang Cheng, Si Wang, Moshi Song, Zunpeng Liu, Ping Liu, Lei Wang, Yanjiang Wang, Qian Zhao, Kaowen Yan, Piu Chan, Weiqi Zhang, Jing Qu, Guang-Hui Liu. DJ-1 is dispensable for human stem cell homeostasis. Protein Cell, 2019, 10(11): 846‒853 https://doi.org/10.1007/s13238-019-00659-9

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Aras S, Bai M, Lee I, Springett R, Huttemann M, Grossman LI (2015) MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. Mitochondrion 20:43–51 CrossRef Google scholar

[2]	Biosa A, Sandrelli F, Beltramini M, Greggio E, Bubacco L, Bisaglia M (2017) Recent findings on the physiological function of DJ-1: beyond Parkinson’s disease. Neurobiol Dis 108:65–72 CrossRef Google scholar

[3]	Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299:256–259 CrossRef Google scholar

[4]	Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP (2006) DJ-1, a cancer- and Parkinson’s disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci USA 103:15091–15096 CrossRef Google scholar

[5]	Damier P, Hirsch EC, Agid Y, Graybiel AM (1999) The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson’s disease. Brain 122(Pt 8):1437–1448 CrossRef Google scholar

[6]	Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H (2015) CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genomewide linkage and sequencing study. Lancet Neurol 14:274–282 CrossRef Google scholar

[7]	Kahle PJ, Waak J, Gasser T (2009) DJ-1 and prevention of oxidative stress in Parkinson’s disease and other age-related disorders. Free Radic Biol Med 47:1354–1361 CrossRef Google scholar

[8]	Nagakubo D, Taira T, Kitaura H, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H (1997) DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun 231:509–513 CrossRef Google scholar

[9]	Oh J, Lee YD, Wagers AJ (2014) Stem cell aging: mechanisms, regulators and therapeutic opportunities. Nat Med 20:870–880 CrossRef Google scholar

[10]	Richarme G, Liu C, Mihoub M, Abdallah J, Leger T, Joly N, Liebart JC, Jurkunas UV, Nadal M, Bouloc P (2017) Guanine glycation repair by DJ-1/Park7 and its bacterial homologs. Science 357:208–211 CrossRef Google scholar

[11]	Sharma N, Rao SP, Kalivendi SV (2019) The deglycase activity of DJ-1 mitigates alpha-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson’s disease. Free Radic Biol Med 135:28–37 CrossRef Google scholar

[12]	Shimojima K, Okumura A, Hayashi M, Kondo T, Inoue H, Yamamoto T (2015) CHCHD2 is down-regulated in neuronal cells differentiated from iPS cells derived from patients with lissencephaly. Genomics 106:196–203 CrossRef Google scholar

[13]	Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H (2004) DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 5:213–218 CrossRef Google scholar

[14]	Zhang W, Qu J, Suzuki K, Liu GH, Izpisua Belmonte JC (2013) Concealing cellular defects in pluripotent stem cells. Trends Cell Biol 23:587–592 CrossRef Google scholar

[15]	Zhang Y, Li Y, Han X, Dong X, Yan X, Xing Q (2018) Elevated expression of DJ-1 (encoded by the human PARK7 gene) protects neuronal cells from sevoflurane-induced neurotoxicity. Cell Stress Chaperones 23:967–974 CrossRef Google scholar