Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding

Yinan Jiang, Xinquan Wang

PDF(2116 KB)
PDF(2116 KB)
Protein Cell ›› 2019, Vol. 10 ›› Issue (9) : 681-687. DOI: 10.1007/s13238-018-0598-4
LETTER
LETTER

Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding

Author information +
History +

Cite this article

Download citation ▾
Yinan Jiang, Xinquan Wang. Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding. Protein Cell, 2019, 10(9): 681‒687 https://doi.org/10.1007/s13238-018-0598-4

References

[1]
Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P (2012) Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency. Science 337:1684–1688
CrossRef Google scholar
[2]
Farrell PJ, Broeze RJ, Lengyel P (1979) Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells. Nature 279:523–525
CrossRef Google scholar
[3]
Guan R, Ma LC, Leonard PG, Amer BR, Sridharan H, Zhao C, Krug RM, Montelione GT (2011) Structural basis for the sequencespecific recognition of human ISG15 by the NS1 protein of influenza B virus. Proc Natl Acad Sci USA 108:13468–13473
CrossRef Google scholar
[4]
Haas AL, Ahrens P, Bright PM, Ankel H (1987) Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem 262:11315–11323
[5]
Hermann M, Bogunovic D (2016) ISG15. In Sickness and in Health. Trends Immunol 38:79–93
CrossRef Google scholar
[6]
Lai C, Struckhoff JJ, Schneider J, Martinez-Sobrido L, Wolff T, Garcia-Sastre A, Zhang DE, Lenschow DJ (2009) Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. J Virol 83:1147–1151
CrossRef Google scholar
[7]
Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, Garcia-Sastre A (2007) IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci USA 104:1371–1376
CrossRef Google scholar
[8]
Li L, Wang D, Jiang Y, Sun J, Zhang S, Chen Y, Wang X (2011) Crystal structure of human ISG15 protein in complex with influenza B virus NS1B. J Biol Chem 286:30258–30262
CrossRef Google scholar
[9]
Narasimhan J, Wang M, Fu Z, Klein JM, Haas AL, Kim JJ (2005) Crystal structure of the interferon-induced ubiquitin-like protein ISG15. J Biol Chem 280:27356–27365
CrossRef Google scholar
[10]
Schoggins JW, Rice CM (2011) Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 1:519–525
CrossRef Google scholar
[11]
Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M (2016) ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun 7:11496
CrossRef Google scholar
[12]
Sridharan H, Zhao C, Krug RM (2010) Species specificity of the NS1 protein of influenza B virus: NS1 binds only human and nonhuman primate ubiquitin-like ISG15 proteins. J Biol Chem 285:7852–7856
CrossRef Google scholar
[13]
Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, Garcia-Sastre A (2010) Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein. J Virol 84:5423–5430
CrossRef Google scholar
[14]
Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C, Volpi S, Li Z, Sanal O, Mansouri D (2015) Human intracellular ISG15 prevents interferon-alpha/beta overamplification and auto-inflammation. Nature 517:89–93
CrossRef Google scholar
[15]
Zhao C, Sridharan H, Chen R, Baker DP, Wang S, Krug RM (2016) Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins. Nat Commun 7:12754
CrossRef Google scholar

RIGHTS & PERMISSIONS

2018 The Author(s) 2018. This article is an open access publication
AI Summary AI Mindmap
PDF(2116 KB)

Accesses

Citations

Detail

Sections
Recommended

/