Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding

References

[1] Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P (2012) Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency. Science 337:1684–1688

[2] Farrell PJ, Broeze RJ, Lengyel P (1979) Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells. Nature 279:523–525

[3] Guan R, Ma LC, Leonard PG, Amer BR, Sridharan H, Zhao C, Krug RM, Montelione GT (2011) Structural basis for the sequencespecific recognition of human ISG15 by the NS1 protein of influenza B virus. Proc Natl Acad Sci USA 108:13468–13473

[4] Haas AL, Ahrens P, Bright PM, Ankel H (1987) Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem 262:11315–11323

[5] Hermann M, Bogunovic D (2016) ISG15. In Sickness and in Health. Trends Immunol 38:79–93

[6] Lai C, Struckhoff JJ, Schneider J, Martinez-Sobrido L, Wolff T, Garcia-Sastre A, Zhang DE, Lenschow DJ (2009) Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. J Virol 83:1147–1151

[7] Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, Garcia-Sastre A (2007) IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci USA 104:1371–1376

[8] Li L, Wang D, Jiang Y, Sun J, Zhang S, Chen Y, Wang X (2011) Crystal structure of human ISG15 protein in complex with influenza B virus NS1B. J Biol Chem 286:30258–30262

[9] Narasimhan J, Wang M, Fu Z, Klein JM, Haas AL, Kim JJ (2005) Crystal structure of the interferon-induced ubiquitin-like protein ISG15. J Biol Chem 280:27356–27365

[10] Schoggins JW, Rice CM (2011) Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 1:519–525

[11] Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M (2016) ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun 7:11496

[12] Sridharan H, Zhao C, Krug RM (2010) Species specificity of the NS1 protein of influenza B virus: NS1 binds only human and nonhuman primate ubiquitin-like ISG15 proteins. J Biol Chem 285:7852–7856

[13] Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, Garcia-Sastre A (2010) Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein. J Virol 84:5423–5430

[14] Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C, Volpi S, Li Z, Sanal O, Mansouri D (2015) Human intracellular ISG15 prevents interferon-alpha/beta overamplification and auto-inflammation. Nature 517:89–93

[15] Zhao C, Sridharan H, Chen R, Baker DP, Wang S, Krug RM (2016) Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins. Nat Commun 7:12754

RIGHTS & PERMISSIONS

The Author(s) 2018. This article is an open access publication