Help, hope and hype: ethical considerations of human microbiome research and applications
Yonghui Ma, Hua Chen, Canhui Lan, Jianlin Ren
Help, hope and hype: ethical considerations of human microbiome research and applications
[1] |
Balskus EP (2016) Addressing infectious disease challenges by investigating microbiomes. ACS Infect Dis 2(7):453–455
CrossRef
Google scholar
|
[2] |
Bannaga AS, Selinger CP (2015) Inflammatory bowel disease and anxiety: links, risks, and challenges faced. Clin Exp Gastroenterol 8:111–117
|
[3] |
Best is yet to come (2011) Nature 470:140. https://www.nature.com/articles/470140a
|
[4] |
Bik EM (2016) The hoops, hopes, and hypes of human microbiome research. Yale J Biol Med 89(3):363–373
|
[5] |
Bledsoe MJ (2017) Ethical legal and social issues of biobanking: past, present, and future. Biopreserv Biobank 15(2):142–147
CrossRef
Google scholar
|
[6] |
Bolan S, Seshadri B, Talley NJ, Naidu R (2016) Bio-banking gut microbiome samples. EMBO Rep 17(7):929–930
CrossRef
Google scholar
|
[7] |
Borody TJ, Campbell J (2012) Fecal microbiota transplantation: techniques, applications, and issues. Gastroenterol Clin N Am 41(4):781–803
CrossRef
Google scholar
|
[8] |
Brownsword R, Wale J (2017) The right to know and the right not to know revisited: part one. Asian Bioeth Rev 9(1):3–18
|
[9] |
Burke W, Burton H, Hall AE, Karmali M, Khoury MJ, Knoppers B, Meslin EM, Stanley F, Wright CF, Zimmern RL (2010) Extending the reach of public health genomics: what should be the agenda for public health in an era of genome-based and “personalized” medicine? Genet Med 12(12):785–791
CrossRef
Google scholar
|
[10] |
Cambon-Thomsen A (2004) The social and ethical issues of postgenomic human biobanks. Nat Rev Genet 5(11):866–873
CrossRef
Google scholar
|
[11] |
Cammarota G, Ianiro G, Gasbarrini A (2014) Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review. J Clin Gastroenterol 48(8):693–702
CrossRef
Google scholar
|
[12] |
Caulfield T (2007) Biobanks and blanket consent: the proper place of the public good and public perception rationales. King’s Law J 18(2):209–226
CrossRef
Google scholar
|
[13] |
Chen Y, Blaser MJ (2007) Inverse associations of Helicobacter pylori with asthma and allergy. Arch Intern Med 167(8):821–827
CrossRef
Google scholar
|
[14] |
Chu DM, Ma J, Prince AL, Antony KM, Seferovic MD, Aagaard KM (2017) Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery. Nat Med 23:314
CrossRef
Google scholar
|
[15] |
Chuong KH, Hwang DM, Tullis DE, Waters VJ, Yau YC, Guttman DS, O’Doherty KC (2017) Navigating social and ethical challenges of biobanking for human microbiome research. BMC Med Ethics 18(1):1
CrossRef
Google scholar
|
[16] |
Collins FS (1999) Shattuck lecture–medical and societal consequences of the human genome project. N Engl J Med 341(1):28–37
CrossRef
Google scholar
|
[17] |
Costello SP, Tucker EC, La Brooy J, Schoeman MN, Andrews JM (2016) Establishing a fecal microbiota transplant service for the treatment of clostridium difficile infection. Clin Infect Dis 62(7):908–914
CrossRef
Google scholar
|
[18] |
Cryan JF, Dinan TG (2012) Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 13(10):701–712
CrossRef
Google scholar
|
[19] |
Cunnington AJ, Sim K, Deierl A, Kroll JS, Brannigan E, Darby J (2016) “Vaginal seeding” of infants born by caesarean section. BMJ 352
CrossRef
Google scholar
|
[20] |
Dethlefsen L, McFall-Ngai M, Relman DA (2007) An ecological and evolutionary perspective on human–microbe mutualism and disease. Nature 449:811
CrossRef
Google scholar
|
[21] |
Dominguez-Bello MG, Blaser MJ (2011) The human microbiota as a marker for migrations of individuals and populations. Ann Rev Anthropol 40(1):451–474
CrossRef
Google scholar
|
[22] |
Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, Knight R (2010) Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci 107(26):11971
CrossRef
Google scholar
|
[23] |
Emanuel EJ, Wendler D, Grady C (2000) What makes clinical research ethical? Jama 283(20):2701–2711
CrossRef
Google scholar
|
[24] |
Francis LP, Battin MP, Jacobson JA, Smith CB, Botkin J (2005) How infectious diseases got left out–and what this omission might have meant for bioethics. Bioethics 19(4):307–322
CrossRef
Google scholar
|
[25] |
Franzosa EA, Huang K, Meadow JF, Gevers D, Lemon KP, Bohannan BJ (2015) Identifying personal microbiomes using metagenomic codes. Proc Natl Acad Sci USA, 112
CrossRef
Google scholar
|
[26] |
Gligorov N (2013) Privacy, confidentiality, and new ways of knowing more. In: The human microbiome: Ethical, legal and social concerns (Edited by Rosamond Rhodes, Nada Gligorov, Abraham Paul Schwab). Oxford University Press
|
[27] |
Gligorov N, Azzouni J, Lackey DP, Zweig A (2013) Personal Identity: our microbes, ourselves.In: The human microbiome: ethical, legal and social concerns, Edited by Prosamond Rhodes, Nada Gligorov, And Abraham Paul Schwab, Oxford University Press
|
[28] |
Hampton-Marcell JT, Lopez JV, Gilbert JA (2017) The human microbiome: an emerging tool in forensics. Microb Biotechnol 10(2):228–230
CrossRef
Google scholar
|
[29] |
Hanage WP (2014) Microbiology: microbiome science needs a healthy dose of scepticism. Nature 512(7514):247–248
CrossRef
Google scholar
|
[30] |
Harrison KL, Farrell RM, Brinich MA, Highland J, Mercer M, McCormick JB, Tilburt J, Geller G, Marshall P, Sharp RR (2015) ‘Someone should oversee it’: patient perspectives on the ethical issues arising with the regulation of probiotics. Health Expect 18(2):250–261
CrossRef
Google scholar
|
[31] |
Hawkins AK, O’Doherty KC (2011) “Who owns your poop?”: insights regarding the intersection of human microbiome research and the ELSI aspects of biobanking and related studies. BMC Med Genom 4:72
CrossRef
Google scholar
|
[32] |
Honey K (2008) Good bugs, bad bugs: learning what we can from the microorganisms that colonize our bodies. J Clin Invest 118(12):3817
CrossRef
Google scholar
|
[33] |
Hutter T, Gimbert C, Bouchard F, Lapointe F-J (2015) Being human is a gut feeling. Microbiome 3:9
CrossRef
Google scholar
|
[34] |
Juengst ET, Settersten RA, Fishman JR, McGowan ML (2012) After the revolution? Ethical and social challenges in ‘personalized genomic medicine’. Pers Med 9(4):429–439
CrossRef
Google scholar
|
[35] |
Lederberg J (2006) The microbe’s contribution to biology–50 years after. Int Microb 9(3):155–156
|
[36] |
Lu C, Sang J, He H, Wan X, Lin Y, Li L, Li Y, Yu C (2016) Probiotic supplementation does not improve eradication rate of Helicobacter pylori infection compared to placebo based on standard therapy: a meta-analysis. Sci Rep 6:23522
CrossRef
Google scholar
|
[37] |
Ma B, Forney LJ, Ravel J (2012) The vaginal microbiome: rethinking health and diseases. Ann Rev Microbiol 66:371–389
CrossRef
Google scholar
|
[38] |
Ma Y, Liu J, Rhodes C, Nie Y, Zhang F (2017a) Ethical issues in fecal microbiota transplantation in practice. Am J Bioeth 17(5):34–45
CrossRef
Google scholar
|
[39] |
Ma Y, Chen H, Lei R, Ren J (2017b) Biobanking for human microbiome research: promise, risks, and ethics. Asian Bioeth Rev 9(4):311–324
|
[40] |
Ma Y, Yang J, Cui B, Xu H, Xiao C, Zhang F (2017c) How Chinese clinicians face ethical and social challenges in fecal microbiota transplantation: a questionnaire study. BMC Med Ethics 18(1):39
CrossRef
Google scholar
|
[41] |
McGuire AL, Colgrove J, Whitney SN, Diaz CM, Bustillos D, Versalovic J (2008) Ethical, legal, and social considerations in conducting the human microbiome project. Genome Res 18(12):1861–1864
CrossRef
Google scholar
|
[42] |
McGuire AL, Achenbaum LS, Whitney SN, Slashinski MJ, Versalovic J, Keitel WA, McCurdy SA (2012) Perspectives on human microbiome research ethics. J Empir Res Hum Res Ethics 7(3):1–14
CrossRef
Google scholar
|
[43] |
Meadow JF, Altrichter AE, Bateman AC, Stenson J, Brown GZ, Green JL, Bohannan BJ (2015) Humans differ in their personal microbial cloud. PeerJ 3:e1258
CrossRef
Google scholar
|
[44] |
Merlo G, Graves N, Brain D, Connelly L (2016) Economic evaluation of fecal microbiota transplantation for the treatment of recurrent clostridium difficile infection in Australia. J Gastroenterol Hepatol 31(12):1927–1932
CrossRef
Google scholar
|
[45] |
Nettleton S (2013) The sociology of health and illness, 3rd edn. Polity, Malden
|
[46] |
Nguyen TL, Vieira-Silva S, Liston A, Raes J (2015) How informative is the mouse for human gut microbiota research? Dis Models Mech 8(1):1–16
CrossRef
Google scholar
|
[47] |
O’Doherty KC, Virani A, Wilcox ES (2016) The human microbiome and public health: social and ethical considerations. Am J Public Health 106(3):414–420
CrossRef
Google scholar
|
[48] |
Oh B, Kim BS, Kim JW, Kim JS, Koh SJ, Kim BG, Lee KL, Chun J (2016) The effect of probiotics on gut microbiota during the helicobacter pylori eradication: randomized controlled trial. Helicobacter 21(3):165–174
CrossRef
Google scholar
|
[49] |
Paramsothy S, Borody TJ, Lin E, Finlayson S, Walsh AJ, Samuel D, van den Bogaerde J, Leong RW, Connor S, Ng W
CrossRef
Google scholar
|
[50] |
Ravitsky V, Wilfond BS (2006) Disclosing individual genetic results to research participants. Am J Bioeth 6(6):8–17
CrossRef
Google scholar
|
[51] |
Rhodes R (2013) Introduction: looking back and looking forward.In: The human microbiome: ethical, legal and social concerns, Edited by Prosamond Rhodes, Nada Gligorov, And Abraham Paul Schwab, Oxford University Press
|
[52] |
Rhodes R (2016) Ethical issues in microbiome research and medicine. BMC Med 14(1):156
CrossRef
Google scholar
|
[53] |
Rhodes R, Azzouni J, Baumrin SB, Benkov K, Blaser MJ, Brenner B, Dauben JW, Earle WJ, Frank L, Gligorov N
CrossRef
Google scholar
|
[54] |
Rhodes R, Baumrin SB, Blaser MJ, Earle WJ, Indyk D, Ethylin WJ, Moros DA, Richardson LD, Sacks HS (2013) Public health and research on populations.In: The human microbiome: ethical, legal and social concerns, Edited by Prosamond Rhodes, Nada Gligorov, And Abraham Paul Schwab, Oxford University Press
|
[55] |
Rodriguez JM, Murphy K, Stanton C, Ross RP, Kober OI, Juge N, Avershina E, Rudi K, Narbad A, Jenmalm MC
CrossRef
Google scholar
|
[56] |
Rosamond Rhodes MJB, Dauben JW, Frank LE, Moros DE, Philpott S (2013) Research Ethics. The human microbiome: ethical, legal and social concerns, Edited by Prosamond Rhodes, Nada Gligorov, And Abraham Paul Schwab, Oxford University Press
|
[57] |
Rubin DT, Becker S, Siegler M (2014) Ethical considerations for clinical trials in inflammatory bowel disease. Gastroenterol Hepatol 10(1):37–41
|
[58] |
Ruth R (1986) Faden TLB: a history and theory of informed consent. Oxford University Press, New York
|
[59] |
Sanmiguel C, Gupta A, Mayer EA (2015) Gut microbiome and obesity: a plausible explanation for obesity. Curr Obes Rep 4(2):250–261
CrossRef
Google scholar
|
[60] |
Schmedes SE, Sajantila A, Budowle B (2016) Expansion of Microbial Forensics. J Clin Microb 54(8):1964–1974
CrossRef
Google scholar
|
[61] |
Schulfer A, Blaser MJ (2015) Risks of antibiotic exposures early in life on the developing microbiome. PLoS Pathog 11(7):e1004903
CrossRef
Google scholar
|
[62] |
Schwab AP, Brenner B, Goldfarb J, Hirschhorn R, Philpott S (2013) Biobanks and the human microbiome. In: Rhodes R, Gligorov N, Schwab AP (eds) The human microbiome: ethical, legal and social concerns. Oxford University Press, New York, pp 182–207
|
[63] |
Schwarz S, Morelli G, Kusecek B, Manica A, Balloux F, Owen RJ, Graham DY, van der Merwe S, Achtman M, Suerbaum S (2008) Horizontal versus familial transmission of Helicobacter pylori. PLoS Pathog 4(10):e1000180
CrossRef
Google scholar
|
[64] |
Seeding V (2017) Committee opinion No. 725. American College of obstetricians and gynecologists. Obstet Gynecol 130:e274–e278
|
[65] |
Senok AC, Ismaeel AY, Botta GA (2005) Probiotics: facts and myths. Clin Microbiol Infect 11(12):958–966
CrossRef
Google scholar
|
[66] |
Sharp RR, Achkar J-P, Brinich MA, Farrell RM (2009) Helping patients make informed choices about probiotics: a need for research. Am J Gastroenterol 104(4):809–813
CrossRef
Google scholar
|
[67] |
Slashinski MJ, McCurdy SA, Achenbaum LS, Whitney SN, McGuire AL (2012) “Snake-oil”, “quack medicine”, and “industrially cultured organisms:” biovalue and the commercialization of human microbiome research. BMC Med Ethics 13:28
CrossRef
Google scholar
|
[68] |
Surawicz CM, Brandt LJ, Binion DG, Ananthakrishnan AN, Curry SR, Gilligan PH, McFarland LV, Mellow M, Zuckerbraun BS (2013) Guidelines for diagnosis, treatment, and prevention of clostridium difficile infections. Am J Gastroenterol 108(4):478–498
CrossRef
Google scholar
|
[69] |
Terveer EM, van Beurden YH, Goorhuis A, Seegers JFML, Bauer MP, van Nood E, Dijkgraaf MGW, Mulder CJJ, Vandenbroucke-Grauls CMJE, Verspaget HW
CrossRef
Google scholar
|
[70] |
Torrey FE, Yolken RH (2005) Beasts of the earth: animals, humans, and disease.In: pISCATAWAY, NJ: Rutgers University Press
|
[71] |
Tosh PK, McDonald LC (2012) Infection control in the multidrugresistant era: tending the human microbiome. Clin Infect Dis 54(5):707–713
CrossRef
Google scholar
|
[72] |
Tridico SR, Murray DC, Addison J, Kirkbride KP, Bunce M (2014) Metagenomic analyses of bacteria on human hairs: a qualitative assessment for applications in forensic science. Investig Genet 5(1):1–13
CrossRef
Google scholar
|
[73] |
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP
CrossRef
Google scholar
|
[74] |
van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, Bartelsman JFWM, Tijssen JGP
CrossRef
Google scholar
|
[75] |
Varier RU, Biltaji E, Smith KJ, Roberts MS, Kyle Jensen M, LaFleur J, Nelson RE (2015) Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection. Infect Control Hosp Epidemiol 36(4):438–444
CrossRef
Google scholar
|
[76] |
Walter J, Ley R (2011) The human gut microbiome: ecology and recent evolutionary changes. Annu Rev Microbiol 65:411–429
CrossRef
Google scholar
|
[77] |
Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu X, Zeng L, Chen J, Fan S, Du X
CrossRef
Google scholar
|
/
〈 | 〉 |