Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers

Zhifei Li , Xueliang Ge , Yixiao Zhang , Lvqin Zheng , Suparna Sanyal , Ning Gao

Protein Cell ›› 2018, Vol. 9 ›› Issue (4) : 384 -388.

PDF (1839KB)
Protein Cell ›› 2018, Vol. 9 ›› Issue (4) : 384 -388. DOI: 10.1007/s13238-017-0456-9
LETTER
LETTER

Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers

Author information +
History +
PDF (1839KB)

Cite this article

Download citation ▾
Zhifei Li, Xueliang Ge, Yixiao Zhang, Lvqin Zheng, Suparna Sanyal, Ning Gao. Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers. Protein Cell, 2018, 9(4): 384-388 DOI:10.1007/s13238-017-0456-9

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Ben-Shem A, Garreau de Loubresse N, Melnikov S, Jenner L, Yusupova G, Yusupov M (2011) The structure of the eukaryotic ribosome at 3.0 A resolution. Science 334:1524–1529

[2]

Byrgazov K, Grishkovskaya I, Arenz S, Coudevylle N, Temmel H, Wilson DN, Djinovic-Carugo K, Moll I (2015) Structural basis for the interaction of protein S1 with the Escherichia coli ribosome. Nucleic Acids Res 43:661–673

[3]

Cortes T, Schubert OT, Rose G, Arnvig KB, Comas I, Aebersold R, Young DB (2013) Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis. Cell Rep 5:1121–1131

[4]

Hentschel J, Burnside C, Mignot I, Leibundgut M, Boehringer D, Ban N (2017) The complete structure of the mycobacterium smegmatis 70S ribosome. Cell Rep 20:149–160

[5]

Jenner L, Demeshkina N, Yusupova G, Yusupov M (2010) Structural rearrangements of the ribosome at the tRNA proofreading step. Nat Struct Mol Biol 17:1072–1076

[6]

Khusainov I, Vicens Q, Bochler A, Grosse F, Myasnikov A, Menetret JF, Chicher J, Marzi S, Romby P, Yusupova G (2016) Structure of the 70S ribosome from human pathogen Staphylococcus aureus. Nucleic Acids Res 44:10491–10504

[7]

Li X, Sun Q, Jiang C, Yang K, Hung LW, Zhang J, Sacchettini JC (2015) Structure of ribosomal silencing factor bound to mycobacterium tuberculosis ribosome. Structure 23:1858–1865

[8]

Pulk A, Cate JH (2013) Control of ribosomal subunit rotation by elongation factor G. Science 340:1235970

[9]

Ramakrishnan V (2014) The ribosome emerges from a black box. Cell 159:979–984

[10]

Schmalisch M, Langbein I, Stulke J (2002) The general stress protein Ctc of Bacillus subtilis is a ribosomal protein. J Mol Microbiol Biotechnol 4:495–501

[11]

Selmer M, Dunham CM, Murphy FV, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V (2006) Structure of the 70S ribosome complexed with mRNA and tRNA. Science 313:1935–1942

[12]

Shasmal M, Sengupta J (2012) Structural diversity in bacterial ribosomes: mycobacterial 70S ribosome structure reveals novel features. PLoS ONE 7:e31742

[13]

Shell SS, Wang J, Lapierre P, Mir M, Chase MR, Pyle MM, Gawande R, Ahmad R, Sarracino DA, Ioerger TR (2015) Leaderless transcripts and small proteins are common features of the mycobacterial translational landscape. PLoS Genet 11:e1005641

[14]

Wilson DN (2014) Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Nat Rev Microbiol 12:35–48

[15]

Yusupova G, Yusupov M (2017) Crystal structure of eukaryotic ribosome and its complexes with inhibitors. Philos Trans R Soc Lond B Biol Sci372

RIGHTS & PERMISSIONS

The Author(s) 2017. This article is an open access publication

AI Summary AI Mindmap
PDF (1839KB)

Supplementary files

PAC-0384-17226-GN_suppl_1

858

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/