The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival

Shilei Zhang, Deng Pan, Xin-Ming Jia, Xin Lin, Xueqiang Zhao

PDF(2155 KB)
PDF(2155 KB)
Protein Cell ›› 2017, Vol. 8 ›› Issue (11) : 856-860. DOI: 10.1007/s13238-017-0441-3
LETTER
LETTER

The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival

Author information +
History +

Cite this article

Download citation ▾
Shilei Zhang, Deng Pan, Xin-Ming Jia, Xin Lin, Xueqiang Zhao. The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival. Protein Cell, 2017, 8(11): 856‒860 https://doi.org/10.1007/s13238-017-0441-3

References

[1]
BitonS, AshkenaziA (2011) NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling.Cell145:92–103
CrossRef Google scholar
[2]
BlonskaM, LinX (2011) NF-kappaB signaling pathways regulated by CARMA family of scaffold proteins.Cell Res21:55–70
CrossRef Google scholar
[3]
Diaz BessoneMI, BerardiDE, CampodonicoPB, TodaroLB, LothsteinL, de KierBal, JoffeED, UrtregerAJ (2011) Involvement of PKC delta (PKCdelta) in the resistance against different doxorubicin analogs.Breast Cancer Res Treat126:577–587
CrossRef Google scholar
[4]
GrabinerBC, BlonskaM, LinPC, YouY, WangD, SunJ, DarnayBG, DongC, LinX (2007) CARMA3 deficiency abrogates G proteincoupled receptor-induced NF-{kappa}B activation.Genes Dev21:984–996
CrossRef Google scholar
[5]
HinzM, StilmannM, ArslanSC, KhannaKK, DittmarG, ScheidereitC (2010) A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation.Mol Cell40:63–74
CrossRef Google scholar
[6]
JiangT, GrabinerB, ZhuY, JiangC, LiH, YouY, LangJ, HungMC, LinX (2011) CARMA3 is crucial for EGFR-Induced activation of NF-kappaB and tumor progression.Cancer Res71:2183–2192
CrossRef Google scholar
[7]
JiangC, ZhouZ, QuanY, ZhangS, WangT, ZhaoX, MorrisonC, HeiseMT, HeW, MillerMS (2016) CARMA3 is a host factor regulating the balance of inflammatory and antiviral responses against viral infection.Cell Rep14:2389–2401
CrossRef Google scholar
[8]
KatoT Jr, DelhaseM, HoffmannA, KarinM (2003) CK2 is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response.Mol Cell12:829–839
CrossRef Google scholar
[9]
LiN, BaninS, OuyangH, LiGC, CourtoisG, ShilohY, KarinM, RotmanG (2001) ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks.J Biol Chem276:8898–8903
CrossRef Google scholar
[10]
LiZ, QuL, DongQ, HuangB, LiH, TangZ, XuY, LuoW, LiuL, QiuX (2012) Overexpression of CARMA3 in non-small-cell lung cancer is linked for tumor progression.PLoS ONE7:e36903
CrossRef Google scholar
[11]
MahanivongC, ChenHM, YeeSW, PanZK, DongZ, HuangS (2008) Protein kinase C alpha-CARMA3 signaling axis links Ras to NF-kappa B for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells.Oncogene27:1273–1280
CrossRef Google scholar
[12]
PanD, ZhuY, ZhouZ, WangT, YouH, JiangC, LinX (2016) The CBM complex underwrites NF-kappaB activation to promote HER2-associated tumor malignancy.Mol Cancer Res14:93–102
CrossRef Google scholar
[13]
PomerantzJL, DennyEM, BaltimoreD (2002) CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.EMBO J21:5184–5194
CrossRef Google scholar
[14]
WangD, YouY, CaseSM, McAllister-LucasLM, WangL, DiStefanoPS, NunezG, BertinJ, LinX (2002) A requirement for CARMA1 in TCR-induced NF-kappa B activation.Nat Immunol3:830–835
CrossRef Google scholar
[15]
WuZH, WongET, ShiY, NiuJ, ChenZ, MiyamotoS, TergaonkarV (2010) ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.Mol Cell40:75–86
CrossRef Google scholar

RIGHTS & PERMISSIONS

2017 The Author(s) 2017. This article is an open access publication
AI Summary AI Mindmap
PDF(2155 KB)

Accesses

Citations

Detail

Sections
Recommended

/